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J-GLOBAL ID：201802288140526662   Reference number：18A0482273

Knockout of the interleukin-36 receptor protects against renal ischemia-reperfusion injury by reduction of proinflammatory cytokines

インターロイキン36受容体のノックアウトは炎症誘発性サイトカインの還元による腎臓虚血-再潅流障害から保護する【Powered by NICT】

Author (14)： Nishikawa Hirofumi (Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Taniguchi Yoshinori (Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Matsumoto Tatsuki (Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Arima Naoki (Center for Innovative and Translational Medicine, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Masaki Mamoru (Center for Innovative and Translational Medicine, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Shimamura Yoshiko (Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Inoue Kosuke (Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Horino Taro (Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Fujimoto Shimpei (Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Ohko Kentaro (Department of Dermatology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Komatsu Toshihiro (Department of Immunology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Udaka Keiko (Department of Immunology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Sano Shigetoshi (Department of Dermatology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan) ,  Terada Yoshio (Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan)
Material： Kidney International  (Kidney Int)
Volume： 93  Issue： 3  Page： 599-614  Publication year： 2018 
JST Material Number： E0559B  ISSN： 0085-2538  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： IL-36, a newly named member of...

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Thesaurus term： immunohistochemistry ,  kidney tubule ,  knockout mouse ,  *receptor ,  NF-kappaB ,  pathogenesis ,  *ischemia ,  mRNA ,  Plasma ,  TNF alpha ,  phosphorylation ,  proximal renal tubule ,  interleukin 6 ,  urea nitrogen ,  *inflammatory cytokine ,  laboratory animal ,  Mus musculus

Author keywords (5)： acute kidney injury ,  cytokine ,  IL-36 ,  IL-36 receptor ,  ischemia-reperfusion injury

JST classification (2)： Basic medicine on urogenital system  (GM01020T) ,  Biological function  (EB03040U)

Terms in the title (7)： インターロイキン36 ,  受容体 ,  ノックアウト ,  炎症誘発性サイトカイン ,  還元 ,  腎臓 ,  虚血-再潅流障害