Art

J-GLOBAL ID：201802288350060731   Reference number：18A0124769

NK cell and IFN signatures are positive prognostic biomarkers for resectable pancreatic cancer

NK細胞とIFNシグネチャーは切除可能な膵臓癌のための正の予後バイオマーカーである【Powered by NICT】

Author (23)： Hoshikawa Mayumi (Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Aoki Taku (Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Aoki Taku (Second Department of Surgery, Dokkyo Medical University, Mibu, Tochigi 321-0293, Japan) ,  Matsushita Hirokazu (Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Matsushita Hirokazu (Cancer Immunology Data Multi-level Integration Unit, Medical Science Innovation Hub Program, RIKEN, Nihonbashi, Chuo-ku, Tokyo 103-0027, Japan) ,  Karasaki Takahiro (Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Hosoi Akihiro (Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Hosoi Akihiro (Medinet Co. Ltd., Yokohama, Kanagawa 222-0033, Japan) ,  Odaira Kosuke (Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Odaira Kosuke (Medinet Co. Ltd., Yokohama, Kanagawa 222-0033, Japan) ,  Fujieda Nao (Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Fujieda Nao (Medinet Co. Ltd., Yokohama, Kanagawa 222-0033, Japan) ,  Kobayashi Yukari (Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Kobayashi Yukari (Medinet Co. Ltd., Yokohama, Kanagawa 222-0033, Japan) ,  Kambara Kaori (Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Kambara Kaori (Medinet Co. Ltd., Yokohama, Kanagawa 222-0033, Japan) ,  Ohara Osamu (Department of Technology Development, Kazusa DNA Research Institute, Kisarazu, Chiba 294-0226, Japan) ,  Arita Junichi (Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Hasegawa Kiyoshi (Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Kakimi Kazuhiro (Department of Immunotherapeutics, The University of Tokyo Hospital, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Kakimi Kazuhiro (Cancer Immunology Data Multi-level Integration Unit, Medical Science Innovation Hub Program, RIKEN, Nihonbashi, Chuo-ku, Tokyo 103-0027, Japan) ,  Kokudo Norihiro (Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan) ,  Kokudo Norihiro (National Center for Global Health and Medicine, Shinjuku-ku, Tokyo 162-8655, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 495  Issue： 2  Page： 2058-2065  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： To establish prognostic biomar...

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Thesaurus term： flow cytometry ,  recurrence ,  patient ,  tumor ,  chemokine ,  excision ,  plasma(blood) ,  *NK cell ,  gene expression ,  gene ,  *pancreatic tumor ,  RNA ,  *biomarker
Semi thesaurus term： 免疫細胞 ,  治療標的 , 【Automatic Indexing@JST】

Author keywords (5)： Pancreatic cancer ,  NK cell ,  NGS ,  GSEA ,  IFN signature

JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Cell physiology in general  (EF02010S) ,  Gene expression  (EC02040Q)

Terms in the title (6)： NK細胞 ,  IFN ,  シグネチャー ,  膵臓癌 ,  予後 ,  バイオマーカー