Art

J-GLOBAL ID：201802292210851823   Reference number：18A0952469

Late Relapse after a Sustained Virologic Response at 24 Weeks after Treatment with Daclatasvir and Asunaprevir Combination Therapy for Chronic Hepatitis C Virus Genotype 1b Infection with Liver Cirrhosis

肝硬変を伴う慢性C型肝炎ウイルス遺伝子型1b感染症に対するダクラタスビルおよびアスナプレビル併用療法による治療後24週での持続性ウイルス学的著効後の後期再発

Author (13)： Uojima Haruki (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Murakami Shuko (Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Japan) ,  Nakatani Seigo (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Hidaka Hisashi (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Takeuchi Atsuko (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Tanaka Yoshiaki (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Inoue Tomoyoshi (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Yamane Keiko (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Kubota Kousuke (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Nakazawa Takahide (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Shibuya Akitaka (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan) ,  Tanaka Yasuhito (Department of Virology and Liver Unit, Nagoya City University Graduate School of Medical Sciences, Japan) ,  Koizumi Wasaburo (Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan)
Material： Internal Medicine (Web)  (Intern Med (Web))
Volume： 57  Issue： 7  Page： 951-956(J-STAGE)  Publication year： 2018 
JST Material Number： U0033A  ISSN： 1349-7235  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： Sustained Virologic Response

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Author keywords (5)： asunaprevir ,  daclatasvir ,  interferon-free regimen ,  late relapse ,  liver cirrhosis

JST classification (2)： Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Clinical medicine on digestive system in general  (GH01030P)

Substance index (2)： BMS-650032 ,  BMS-790052

Reference (17)：

• 1. El-Serag HB, Kanwal F, Richardson P, Kramer J. Risk of hepatocellular carcinoma after sustained virological response in Veterans with hepatitis C virus infection. Hepatology 64: 130-137, 2016.
• 2. Holmes JA, Thompson AJ. Interferon-free combination therapies for the treatment of hepatitis C: current insights. Hepat Med 7: 51-70, 2015.
• 3. Formann E, Steindl-Munda P, Hofer H, et al. Long-term follow-up of chronic hepatitis C patients with sustained virological response to various forms of interferon-based anti-viral therapy. Aliment Pharmacol Ther 23: 507-511, 2006.
• 4. Simmons B, Saleem J, Hill A, Riley RD, Cooke GS. Risk of late relapse or reinfection with hepatitis C virus after achieving a sustained virological response: a systematic review and meta-analysis. Clin Infect Dis 62: 683-694, 2016.
• 5. Colson P, Bregigeon S, Tourres C, Solas C, Poizot-Martin I, Tamalet C. Relapse of hepatitis C virus after 14 months of sustained virological response following pegylated-interferon alpha plus ribavirin therapy in a human immunodeficiency virus type 1 infected patient. J Clin Virol 58: 309-314, 2013.

Terms in the title (11)： 肝硬変 ,  慢性C型肝炎 ,  ウイルス ,  遺伝子型1b ,  感染症 ,  ダクラタスビル ,  アスナプレビル ,  併用療法 ,  治療 ,  持続性ウイルス学的著効 ,  後期再発