國吉佳奈子

Research field (1)： Immunology

Research keywords (4)：シグナル伝達 , ウイルス感染 , 炎症反応 , 自然免疫

Research theme for competitive and other funds (7)：

2020 - 2025 Comprehensive understanding of Regnase-1-mediated mRNA surveillance system
2021 - 2024 Identification of novel macrophage subtypes in the liver and comprehensive understanding of their function
2020 - 2023 腫瘍疾患にかかわるマクロファージの探求と解析
2020 - 2021 Integrated understanding of functional features of Regnase -1
2019 - 2021 脳梗塞巣における一酸化窒素合成酵素の役割と機能解析

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Papers (5)：

Katsuhiro Nakagawa, Takanori Matsuki, Liang Zhao, Kanako Kuniyoshi, Hiroki Tanaka, Isao Ebina, Kenta J. Yoshida, Hiroshi Nabeshima, Kiyoharu Fukushima, Hisashi Kanemaru, et al. Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis. International Immunology. 2018. 30. 2. 69-78
Hisashi Kanemaru, Fumihiro Yamane, Kiyoharu Fukushima, Takanori Matsuki, Takahiro Kawasaki, Isao Ebina, Kanako Kuniyoshi, Hiroki Tanaka, Kenta Maruyama, Kazuhiko Maeda, et al. Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017. 114. 35. E7331-E7340
Kanako Kuniyoshi, Osamu Takeuchi, Surya Pandey, Takashi Satoh, Hidenori Iwasaki, Shizuo Akira, Taro Kawai. Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014. 111. 15. 5646-5651
Takuya Uehata, Hidenori Iwasaki, Alexis Vandenbon, Kazufumi Matsushita, Eduardo Hernandez-Cuellar, Kanako Kuniyoshi, Takashi Satoh, Takashi Mino, Yutaka Suzuki, Daron M Standley, et al. Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation. Cell. 2013. 153. 5. 1036-49
Hidenori Iwasaki, Osamu Takeuchi, Shunsuke Teraguchi, Kazufumi Matsushita, Takuya Uehata, Kanako Kuniyoshi, Takashi Satoh, Tatsuya Saitoh, Mutsuyoshi Matsushita, Daron M. Standley, et al. The I kappa B kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1. NATURE IMMUNOLOGY. 2011. 12. 12. 1167-U57

Books (2)：

免疫学update-分子病態の解明と治療への展開-
南山堂 2012
臨床と微生物
近代出版 2009

Lectures and oral presentations (4)：

脳梗塞における一酸化窒素合成酵素の有害な作用
(第48回日本心脈管作動物質学会 2019)
虚血性疾患における一酸化窒素合成酵素の役割
(第三回黒潮カンファレンス 2018)
Pivotal role of MEX3C in RIG-I-mediated antiviral innate immunity
(JSPS Stockholm Simposium 2014)
Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity
(Kyestone symposium 2014)

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國吉 佳奈子

國吉佳奈子