Research theme for competitive and other funds (16)：
2025 - 2028 Development of a sub-GHz ultra-low noise RF synthesizer for use in biomedical EPR spectroscopy
2024 - 2027 Development of PET/EPR functional imaging method for early diagnosis of cancer
2021 - 2025 Development of a portable digital EPR imaging system for biological applications
2021 - 2025 Development of a portable digital EPR imaging system for biological applications
2020 - 2024 Development of a novel ESR oximetry for tumor-therapy-effect prediction
2018 - 2021 Shortening of measurement time for in vivo digital EPR spectrometer
2016 - 2018 Development of digital CW EPR spectrometer for in-vivo applications
2014 - 2018 Development of portable illegal & counterfeit drug detection apparatus using nuclear quadrupole resonance
2014 - 2017 Molecular imaging of brain disease model mice by MRI and EPR imaging
2014 - 2016 Development of low field EPR/NMR co-imaging system for biological samples
2013 - 2015 Simultaneous imaging of multiple bio-functions by EPR imaging method
2012 - 2013 核四極共鳴を用いた覚せい剤非接触検知技術の開発
2011 - 2012 Study on a detection method of illegal drugs using piezoelectric effect
2010 - 2012 Development of high-sensitivity Earth's field NMR・MRI system
2006 - 2008 Electron spin resonance imaging for brain/neuroscience studies
2002 - 2004 電場発光(EL)年代測定法開発と断層への応用
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Papers (65)：
Kazuhiro Kato, Hironobu Yasui, Hideo Sato-Akaba, Miho C Emoto, Hirotada G Fujii, Maciej M Kmiec, Periannan Kuppusamy, Masaki Nagane, Tadashi Yamashita, Osamu Inanami. Non-invasive electron paramagnetic resonance imaging detects tumor redox imbalance induced by ferroptosis. Redox report : communications in free radical research. 2025. 30. 1. 2454887-2454887
Yukihiro Arai, Mai Taguchi, Oki Mitarai, Ichiro Yamaguchi, Hideo Sato-Akaba, Shingo Matsumoto, Minoru Miyake, Hiroshi Hirata. Three-dimensional electron paramagnetic resonance (EPR) imaging of an X-ray-irradiated bovine tooth: A feasibility study. Radiation Measurements. 2025. 181
Hideo Sato-Akaba, Miho C. Emoto, Hirotada G. Fujii. Three-dimensional whole-body imaging of the bioreduction and clearance of nitroxide probes in the thoracic and abdominal regions of mice using a compact and mobile electron paramagnetic resonance imager. Magnetic Resonance in Medicine. 2025
Hinano Mizugaki, Masaki Nagane, Hideo Sato-Akaba, Maciej Kmiec, Periannan Kuppusamy, Hironobu Yasui, Osamu Inanami, Hironobu Murakami, Naoyuki Aihara, Junichi Kamiie, et al. Hypoxia-induced increase in sphingomyelin synthase 2 aggravates ischemic skeletal muscle inflammation. The FEBS journal. 2024
Kazuhiro Kato, Hironobu Yasui, Hideo Sato-Akaba, Miho C Emoto, Hirotada G Fujii, Maciej M Kmiec, Periannan Kuppusamy, Yuki Mizuno, Yuji Kuge, Masaki Nagane, et al. Feasibility study of multimodal imaging for redox status and glucose metabolism in tumor. Free radical biology & medicine. 2024
酒井司, 赤羽英夫. Development of RF phase automatic adjustment for sub-GHz CW-EPR. 電子スピンサイエンス学会年会(CD-ROM). 2024. 63rd
江本美穂, 赤羽英夫, 藤井博匡. Early detection of the oxidative stress change in Alzheimer’s disease model mice by Tempone with EPR imaging system. 電子スピンサイエンス学会年会(CD-ROM). 2024. 63rd
