Research field (3):
Neuroanatomy and physiology
, Cell biology
, Anatomy
Research theme for competitive and other funds (9):
2021 - 2024 細胞の極性を制御する遺伝子の組織、個体での機能とその分子機構の解明
2021 - 2024 膜融合関連分子による細胞の極性形成および細胞増殖の調節機構の解明
2018 - 2021 Analyses of the in vivo roles of genes that regulate cell polarity and the elucidation of their molecular mechanism
2017 - 2020 Functional analysis of SNARE proteins in the formation of epithelial cell polarity.
2015 - 2018 Elucidation of functions of genes regulating cell polarity in vivo.
2014 - 2016 The molecular mechanisms of intracellular membrane fusion on pancreatic endocrine and brain development
2013 - 2016 Disruption of cell polarity influences the secretion of gastrointestinal hormones
2012 - 2015 Analyses of genes involved in cell polarity in tissues and animals in situ
2012 - 2015 Analyses of molecular mechanism of small intestine epithelia formation
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Papers (18):
Yu Zhang, Masataka Kunii, Manabu Taniguchi, Shin-Ichiro Yoshimura, Akihiro Harada. Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024. 44. 27
Akihiro Harada, Masataka Kunii, Kazuo Kurokawa, Takuya Sumi, Satoshi Kanda, Yu Zhang, Satomi Nadanaka, Koichiro M. Hirosawa, Kazuaki Tokunaga, Takuro Tojima, et al. Dynamic movement of the Golgi unit and its glycosylation enzyme zones. Nature Communications. 2024. 15. 1
Ji Wu, Kenta Moriwaki, Tatsuya Asuka, Ritsuko Nakai, Satoshi Kanda, Manabu Taniguchi, Tatsuki Sugiyama, Shin-Ichiro Yoshimura, Masataka Kunii, Takashi Nagasawa, et al. EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts. Blood advances. 2023
Ayano Iwaki, Kenta Moriwaki, Tomoaki Sobajima, Manabu Taniguchi, Shin-Ichiro Yoshimura, Masataka Kunii, Satoshi Kanda, Yoshihiro Kamada, Eiji Miyoshi, Akihiro Harada. Loss of Rab6a in the small intestine causes lipid accumulation and epithelial cell death from lactation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. 34. 7. 9450-9465