Kurihara Sho

クリハラショウ | Kurihara Sho

Research field (1)： Otorhinolaryngology

Research theme for competitive and other funds (11)：

2024 - 2026 Advancing Novel Therapeutic Approaches for Hearing Loss: Harnessing Human iPSC-Derived Otic Organoids and Innovative Drug Discovery Modalities
2023 - 2025 Development of a treatment for hearing loss using human iPS cell-derived otic organoids and novel antisense oligos
2022 - 2025 Integrated understanding of the brain network: from auditory perception
2022 - 2025 再建中耳を対象としたトポロジー最適化法による伝音難聴治療の方針決定システムの構築
2021 - 2024 IoTセンシングとiPS細胞研究の融合による内耳障害の統合的理解と次世代型創薬

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Papers (40)：

Kosuke Wakayama, Sho Kurihara, Yuta Kurashina. Narrow-width surface acoustic wave device-driven olfactory epithelium-targeted intranasal atomization. International journal of pharmaceutics. 2026. 692. 126630-126630
Kanako Muta, Catia Correia-Caeiro, Junichi Hata, Takako Miyabe-Nishiwaki, Sho Kurihara, Yuri Takae, Hirotaka James Okano, Hideyuki Okano, Anne Burrows. Visualization and quantification of facial muscles with 9.4T MRI-DTI in common marmosets (Callithrix jacchus). Royal Society open science. 2025. 12. 11. 251134-251134
Wataru Yamaguchi, Motoki Hirabayashi, Sho Kurihara, Masahiro Takahashi, Tomomi Fukuda, Kazuhisa Yamamoto, Yuika Sakurai, Yutaka Yamamoto. Clinical Outcomes of Transcanal Endoscopic Eustachian Tube Plug Insertion. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 2025
Motoki Hirabayashi, Sho Kurihara, Hajime Shimmura, Yutaka Matsushita, Yutaka Yamamoto, Hiromi Kojima. The bone conduction threshold pattern may help to estimate the pathology underlying conductive hearing loss. Scientific reports. 2025. 15. 1. 35148-35148
Akira Baba, Sho Kurihara, Satoshi Matsushima, Nobuhiro Ogino, Hideomi Yamauchi, Shun Kusada, Shinnosuke Tatedo, Saeko Kubomae, Takara Nakazawa, Masahiro Takahashi, et al. Predicting Mastoid Extension and Complications such as Labyrinthine Fistula and Dural Exposure in Middle Ear Cholesteatoma Using Lesion Size and Detectability on Non-echo-planar Diffusion-weighted MR Imaging. Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine. 2025

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MISC (46)：

高橋昌寛, 石橋直樹, 土田敬介, 中澤宝, 中島隆博, 平林源希, 栗原渉, 山本和央, 山本裕, 小島博己. ナビゲーションシステム補助下経皮的内視鏡下耳科手術(Percutaneous Endoscopic Ear Surgery:PEES). 日本頭頸部外科学会総会ならびに学術講演会プログラム・予稿集. 2024. 33rd (CD-ROM)
Finite element method provides insights into the pathogenesis of conductive hearing loss. 2023. 6. 3. 222-225
Masaomi Motegi, Yutaka Yamamoto, Kotaro Ouchi, Taisuke Akutsu, Takeshi Tada, Sho Kurihara, Masahiro Takahashi, Sayaka Sanpei, Hiromi Sano, Tsunetaro Morino, et al. The impact of middle ear aeration on surgical outcome after intact canal wall tympanoplasty for cholesteatoma. Nippon Jibiinkoka Tokeibugeka Gakkai Kaiho(Tokyo). 2022. 125. 6. 1039-1040
栗原渉, 平林源希, 藤岡正人, 細谷誠, 小島博己. ヒトiPS細胞由来内耳オルガノイドを用いたシスプラチン障害モデルの解析. 日本耳鼻咽喉科頭頸部外科学会会報. 2022. 125. 4. 730-730
栗原渉, 岡野ジェイムス洋尚, 藤岡正人. 小型霊長類コモンマーモセットを用いた聴覚研究. BIO Clinica. 2022. 37. 2. 207-209

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Patents (4)：

音響外傷難聴モデル動物の作製方法及びそれにより作製される音響外傷難聴モデル動物
音響外傷難聴モデル動物の作製用の音響暴露装置
Method for producing acoustic trauma deafness model animal, and acoustic trauma deafness model animal produced by the same
薬物送達用担体

Books (2)：

オルガノイド研究 : 培養・作製、活用、臨床応用
エヌ・ティー・エス 2024 ISBN:9784860438739
耳は悩んでいる
岩波書店 2023 ISBN:9784004320005

Lectures and oral presentations (5)：

Otic Organoids Containing Spiral Ganglion-like Neurons
(2024)
シンポジウム3 「鼻科領域の基礎的な未解決問題に挑む」客観的嗅覚検査方法の開発を目指した神経トラクトグラフィーによる嗅神経の可視化
(第62回日本鼻科学会総会・学術講演会 2023)
Otic organoids containing spiral ganglion-like neurons (Science Spotlight session)
(International Society for Stem Cell Research 2023 Annual Meeting in Boston 2023)
パネルディスカッション「頭頸部外科領域の挑戦的研究」ヒト iPS 細胞由来内耳オルガノイドを用いた薬効評価系の構築と今後の展開
(第32回日本頭頸部外科学会学術講演会 2023)
Establishment of a noise-induced hearing loss model in non-human primates to accelerate translational research.
(4th Annual Meeting of the Society for Bioacoustics 2017)

Education (1)：

2003 - 2009 Jikei University Faculty of Medicine

Work history (3)：

2024/04 - 現在 Stanford University Otolaryngology - Head & Neck Surgery, Stankovic Research Lab
2023/05 - 現在 Jikei University Department of Otorhinolaryngology Head and Neck Surgery Junior Associate Professor
2018/04 - 2023/04 Jikei University Department of Otorhinolaryngology Head and Neck Surgery

Awards (5)：

2023/05 - 日本耳鼻咽喉科頭頸部外科学会日耳鼻研究奨励賞
2022/09 - 東京慈恵会医科大学伊達会賞(2021年度優秀学位論文)
2022/03 - 日本再生医療学会日本再生医療学会奨励賞(臨床部門) ヒトiPS細胞由来内耳オルガノイドを用いた薬剤性蝸牛神経傷害モデルの解析
2020/07 - Japan XR Science Forum 2020 in Midwest Gold Poster Award
2018/05 - East Asian Symposium on Otology Travel Grants

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