Hisayoshi Hayashi

ハヤシヒサヨシ | Hisayoshi Hayashi

Affiliation and department：

Research field (1)： Physiology

Research keywords (11)：栄養素吸収 , 消化管 , Na代謝 , 傍細胞経路 , 陽イオン透過性 , クロージン , タイト結合 , Na依存性栄養素吸収 , SLC26A3 , NaCl 吸収 , NHE3

Research theme for competitive and other funds (10)：

2021 - 2026 Elucidation of the physiological significance of the energy sensing system in the proximal small intestine
2022 - 2024 小腸吸収上皮細胞を構成する膜リン脂質による栄養素吸収機能の制御
2017 - 2020 Elucidation of the physiological relevance of changes in glucose transport mode in the small intestine
2018 - 2019 上皮バリア蛋白質による新規腸管Na代謝調節機構の解明
2013 - 2017 Elucidation of Na+ recycling mechanisms induced by Na-dependent nutrient absorption in the small intestine

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Papers (65)：

林久由, 中村千紗都, 石塚典子, Hempstock Wendy. マウス小腸における絶食と食餌による部位特異的なグルコース吸収調節機構. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-239]
Chisato Nakamura, Noriko Ishizuka, Kanako Yokoyama, Yuyu Yazaki, Fumiya Tatsumi, Naotaka Ikumi, Wendy Hempstock, Akira Ikari, Yuta Yoshino, Hisayoshi Hayashi. Regulatory mechanisms of glucose absorption in the mouse proximal small intestine during fasting and feeding. Scientific Reports. 2023. 13. 1
Wendy Hempstock, Nozomi Nagata, Noriko Ishizuka, Hisayoshi Hayashi. The effect of claudin-15 deletion on cationic selectivity and transport in paracellular pathways of the cecum and large intestine. Scientific reports. 2023. 13. 1. 6799-6799
Noriko Ishizuka, Mina Nagahashi, Yuina Mochida, Wendy Hempstock, Nozomi Nagata, Hisayoshi Hayashi. Na⁺-dependent intestinal glucose absorption mechanisms and its luminal Na⁺ homeostasis across metamorphosis from tadpoles to frogs. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2023
Mikio Furuse, Daiki Nakatsu, Wendy Hempstock, Shiori Sugioka, Noriko Ishizuka, Kyoko Furuse, Taichi Sugawara, Yugo Fukazawa, Hisayoshi Hayashi. Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells. Cell structure and function. 2022

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MISC (21)：

林久由, 石塚典子, 古瀬幹夫. Elucidation of Novel Regulatory Mechanisms of Intestinal Na Metabolism by a Tricellular Tight Junction Protein. ソルト・サイエンス研究財団助成研究報告集 2 医学食品科学編. 2020. 2018
廣田智恵子, 高階優衣, 眞鍋綾, 古川千紗, 石塚典子, 林久由, 田渕圭章, 松永俊之, 五十里彰. アンジオテンシンIIによる結腸食塩吸収の調節におけるクローディンの関与. 日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会講演要旨集. 2020. 2020
Hisayoshi Hayashi, Haruna Tajima, Miki Watanabe, Noriko Ishizuka. Loss of the Tight Junction Protein Claudin 15 Causes Malabsorption of Peptide in Murine Intestine. FASEB JOURNAL. 2016. 30
Yuichi Suzuki, Osamu Ikehara, Hisayoshi Hayashi, Shin-Ichiro Karaki, Atsukazu Kuwahara. Interaction between the protease-signalings and the mucosal nerves in regulation of colonic epithelial Cl- secretion. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S14-S14
Yuichi Suzuki, Osamu Ikehara, Hisayoshi Hayashi. Anion secretion induced by mucosal trypsin in mouse cecum. FASEB JOURNAL. 2011. 25

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Books (1)：

Lectures and oral presentations (46)：

腸塩分吸収の調節における細胞間接着分子クローディン-7の役割
(第67回中部日本生理学会 2020)
消化管NaCl吸収におけるNa+/H+交換輸送体NHE3の役割の検討
(第67回中部日本生理学会 2020)
マウス腸管における三細胞タイト結合タンパク質アンギュリン1の役割の検討
(第67回中部日本生理学会 2020)
Effect of claudin 15 knockout in the murine cecum and the large intestine
(第67回中部日本生理学会 2020)
消化管におけるNaCl吸収輸送体のカップリング機構
(第97回日本生理学会大会 2020)

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Education (2)：

- 1998 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
- 1991 University of Shizuoka School of Food and Nutritional Sciences Department of Food Science

Professional career (1)：

Work history (5)：

2013/06 - 現在 University of Shizuoka School of Food and Nutritional Sciences
2007/04 - 2013/05 University of Shizuoka School of Food and Nutritional Sciences
1998/04 - 2007/03 University of Shizuoka School of Food and Nutritional Sciences
1999/06 - 2002/03 トロント小児病院リサーチフェロー
1991/06 - 1995/06 University of Shizuoka School of Food and Nutritional Sciences

Association Membership(s) (6)：

英国生理学会 , トランスポーター研究会 , 日本栄養・食糧学会 , 米国生理学会 , 日本生化学会 , 日本生理学会

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