Yuqiu Wu

ウーユーチュー | Yuqiu Wu

Affiliation and department：

Research field (3)： Pharmaceuticals - chemistry and drug development , Environmental and pharmaceutical development resources , Neuroscience - general

Research keywords (4)：交感神経 , Natural Product Chemistry , Neuroprotection , Stress

Research theme for competitive and other funds (3)：

2021 - 2024 Roles of brain thromboxane A2 in the major depression-related disorder of glucose metabolism
2020 - 2023 ストレス応答の異常な持続的亢進をもたらす脳内機序の解明
2020 - 2022 Role of prostanoid-related mediators in restraint stress-induced sympathetic activation

Papers (22)：

Naoi M, Wu Y, Shamoto-Nagai M, Maruyama W. Mitochondria in Neuroprotection by Phytochemicals: Bioactive Polyphenols Modulate Mitochondrial Apoptosis System, Function and Structure. International journal of molecular sciences. 2019. 20. 10
Kazumura K, Takeuchi K, Hara A, Miwa T, Hattori M, Wu Y, Morishita N, Tsuchiya H, Osawa T. Rapid on-site dual optical system to measure specific reactive oxygen species (O2-• and OCl-) in a tiny droplet of whole blood. PloS one. 2018. 13. 8. e0200573
Shino Tooriyama, Yuji Mimori, Yuqiu Wu, Noriyuki Kogure, Mariko Kitajima, Hiromitsu Takayama. Asymmetric Total Synthesis of Pentacyclic Indole Alkaloid Andranginine and Absolute Configuration of Natural Product Isolated from Kopsia arborea. ORGANIC LETTERS. 2017. 19. 10. 2722-2725
Yuqiu Wu, Masayo Shamoto-Nagai, Wakako Maruyama, Toshihiko Osawa, Makoto Naoi. Phytochemicals prevent mitochondrial membrane permeabilization and protect SH-SY5Y cells against apoptosis induced by PK11195, a ligand for outer membrane translocator protein. JOURNAL OF NEURAL TRANSMISSION. 2017. 124. 1. 89-98
Mariko Kitajima, Maiko Nakazawa, Yuqiu Wu, Noriyuki Kogure, Rong-Ping Zhang, Hiromitsu Takayama. Kopsiyunnanines L and M, Strychnos-related monoterpenoid indole alkaloids from Yunnan Kopsia arborea. TETRAHEDRON. 2016. 72. 42. 6692-6696

ｍore...

MISC (1)：

Makoto Naoi, Yuqiu Wu, Masayo Shamoto-Nagai, Wakako Maruyama. Bioactive Dietary Compounds Regulate Mitochondrial Apoptosis Signaling in Ambivalent Way to Function as Neuroprotective or Antitumor Agents. Studies in Natural Products Chemistry. 2016. 51. 201-222

Patents (1)：

ミトコンドリア膜透過性の評価方法、ミトコンドリア膜透過性の亢進を抑制する物質のスクリーニング方法、ミトコンドリア膜透過性を亢進する物質のスクリーニング方法、及びミトコンドリア膜透過性の亢進抑制剤

Lectures and oral presentations (1)：

Novel Indole Alkaloids, Kopsiyunnanine A~D from Kopsia officinalis.
(Symposium on the Chemistry of Natural Products 2008)

Professional career (1)：

博士(薬学) (千葉大学)

Awards (2)：

2015/09 - 2015年度日本生薬学会論文賞
2007/04 - 公益財団法人上原記念生命科学財団来日研究生助成金

Association Membership(s) (1)：

日本薬理学会

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