Art

J-GLOBAL ID：201702278527857531   Reference number：17A0925883

Asymmetric Total Synthesis of Pentacyclic Indole Alkaloid Andranginine and Absolute Configuration of Natural Product Isolated from Kopsia arborea

ペンタ環状インドールアルカロイドアンドランギニンの不斉全合成およびKopsia arboreaから単離された天然化合物の絶対配置

Author (6)： TOORIYAMA Shino (Chiba Univ., Chiba, JPN) ,  MIMORI Yuji (Chiba Univ., Chiba, JPN) ,  WU Yuqiu (Chiba Univ., Chiba, JPN) ,  KOGURE Noriyuki (Chiba Univ., Chiba, JPN) ,  KITAJIMA Mariko (Chiba Univ., Chiba, JPN) ,  TAKAYAMA Hiromitsu (Chiba Univ., Chiba, JPN)
Material： Organic Letters  (Org Lett)
Volume： 19  Issue： 10  Page： 2722-2725  Publication year： May. 19, 2017 
JST Material Number： W1171A  ISSN： 1523-7060  CODEN： ORLEF7  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： absolute configuration ,  *indole alkaloid ,  coupling reaction ,  *Diels-Alder reaction ,  Fischer indole synthesis ,  ketone ,  nitrogen heterocyclic compound ,  total synthesis ,  molecular structure ,  chemical synthesis ,  X-ray structural analysis ,  NMR ,  ultraviolet and visible absorption spectrum ,  mixture ,  Apocynaceae ,  oxidation ,  cyclization reaction ,  Morita-Baylis-Hillman Reaction ,  enantiomer mixture ,  Pyridones ,  natural product synthesis ,  asymmetric total synthesis
Semi thesaurus term： Kopsia arborea

JST classification (3)： Condensed derivatives of pyrroles  (CF07077C) ,  Cyclization reaction,ring-opening reaction  (CF02050I) ,  Other natural substances of biological origin  (CF10090R)

Substance index (17)： (14bS,14cR)-14-Benzyl-1,2,9,14,14b,14c-hexahydro-6H,8H-indolo[3,2-d]pyrido[3,2,1-jk][1]benzoazepine-14b-carboxylic acid methyl ester ,  3,8-Dioxo-5,6,7,8,9,10-hexahydro-3H-pyrido[3,2,1-jk][1]benzoazepine-8aβ(11bαH)-carboxylic acid methyl ester ,  (8aS,11bR)-3-Oxo-8-(2-phenylhydrazono)-5,6,7,8,8a,9,10,11b-octahydro-3H-pyrido[3,2,1-jk][1]benzoazepine-8a-carboxylic acid methyl ester ,  (8aS,11bR)-8-(2-Phenylhydrazono)-5,6,7,8,8a,9,10,11b-octahydro-3H-pyrido[3,2,1-jk][1]benzoazepine-8a-carboxylic acid methyl ester ,  8-(2-Benzyl-2-phenylhydrazono)-5,6,7,8,9,10-hexahydro-3H-pyrido[3,2,1-jk][1]benzoazepine-8aβ(11bαH)-carboxylic acid methyl ester ,  3-Oxo-8β-[(4-nitrobenzoyl)oxy]-5,6,7,8,9,10-hexahydro-3H-pyrido[3,2,1-jk][1]benzoazepine-8aβ(11bαH)-carboxylic acid methyl ester ,  (8R,8aS,11bR)-3-Oxo-8-hydroxy-5,6,7,8,8a,9,10,11b-octahydro-3H-pyrido[3,2,1-jk][1]benzoazepine-8a-carboxylic acid methyl ester ,  (9S)-3,9-Epoxy-10,11-dihydrocinchonan-6′-ol ,  1,1-Dimethoxy-4-chlorobutane ,  1-(4,4-Dimethoxybutyl)-5-vinylpyridine-2(1H)-one ,  1-(4-Oxobutyl)-5-vinylpyridine-2(1H)-one ,  (R)-2-Methylene-3-[(4-nitrobenzoyl)oxy]-6-[2-oxo-5-vinylpyridine-1(2H)-yl]hexanoic acid methyl ester ,  (R)-2-Methylene-3-hydroxy-6-[2-oxo-5-vinylpyridine-1(2H)-yl]hexanoic acid 1-(trifluoromethyl)-2,2,2-trifluoroethyl ester ,  2-((R)-1-Hydroxy-4-(2-oxo-1,2-dihydro-5-vinylpyridine-1-yl)butyl)acrylic acid methyl ester ,  5-Vinylpyridine-2(1H)-one ,  1,1,1,3,3,3-Hexafluoroisopropyl acrylate ,  Andranginine

Terms in the title (6)： ペンタ ,  環状 ,  不斉全合成 ,  Kopsia ,  単離 ,  天然化合物