Rchr
J-GLOBAL ID：201901010056711695
Update date: Dec. 25, 2025
Nakata Kazuaki
ナカタ カズアキ | Nakata Kazuaki
Affiliation and department：
Other affiliations (1)：
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National Center for Global Health and Medicine
Research field (1)：
Gastroenterology
Research keywords (2)：
Dietary lipids
, intestinal epithelial cells
Research theme for competitive and other funds (2)：
- 2024 - 2026 食事中脂質クオリティーが組織恒常性維持機構に及ぼす影響とその破綻の分子機構の解明
- 2020 - 2024 若年時の高脂肪食摂取が上皮バリア破綻をもたらす機構と疾患発症における意義の解明
Papers (8)：
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Motoyoshi Nagai, Takuma Okawa, Kazuaki Nakata, Daisuke Takahashi, Reina Miyajima, Hiroaki Shiratori, Daisuke Yamanaka, Atsuo Nakamura, Chinatsu Oyama, Shin-Ichiro Takahashi, et al. Sugar and arginine facilitate oral tolerance by ensuring the functionality of tolerogenic immune cell subsets in the intestine. Cell reports. 2024. 43. 7. 114490-114490
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Hiroaki Shiratori, Kisara M Hattori, Kazuaki Nakata, Takuma Okawa, Seiga Komiyama, Yusuke Kinashi, Yuma Kabumoto, Yuria Kaneko, Motoyoshi Nagai, Tomoko Shindo, et al. Purified diet affects intestinal epithelial proliferation and barrier functions through gut microbial alterations. International immunology. 2024
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Mion Ikegami, Hikari Narabayashi, Kazuaki Nakata, Miyu Yamashita, Yutaka Sugi, Yushiro Fuji, Hiroshi Matsufuji, Gaku Harata, Kazutoyo Yoda, Kenji Miyazawa, et al. Intervention in gut microbiota increases intestinal γ-aminobutyric acid and alleviates anxiety behavior: a possible mechanism via the action on intestinal epithelial cells. Frontiers in cellular and infection microbiology. 2024. 14. 1421791-1421791
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Hikari Narabayashi, Chiharu Koma, Kazuaki Nakata, Mion Ikegami, Yusuke Nakanishi, Jun Ogihara, Masato Tsuda, Akira Hosono, Shigemasa Hanazawa, Kyoko Takahashi. Gut microbiota-dependent adaptor molecule recruits DNA methyltransferase to the TLR4 gene in colonic epithelial cells to suppress inflammatory reactions. Frontiers in molecular biosciences. 2022. 9. 1005136-1005136
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Ryusuke Sumiya, Masayoshi Terayama, Teruki Hagiwara, Kazuaki Nakata, Keigo Sekihara, Satoshi Nagasaka, Hideki Miyazaki, Toru Igari, Kazuhiko Yamada, Yuki I Kawamura. Loss of GSTO2 contributes to cell growth and mitochondria function via the p38 signaling in lung squamous cell carcinoma. Cancer science. 2022. 113. 1. 195-204
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Lectures and oral presentations (9)：
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食事由来脂質による消化管発癌リスクは上皮細胞に保持される
(第98回日本生化学会大会 2025)
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食事性ステアリン酸による腸管腫瘍形成の促進におけるFABP5の役割
(第84回日本癌学会学術総会 2025)
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食事性ステアリン酸は脂肪酸結合タンパク質5型を介して腸管腫瘍形成を促進する
(第83回 日本癌学会学術総会 2024)
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DIETARY STEARIC ACID PROMOTES EPITHELIAL CELL PROLIFERATION AND TUMORIGENESIS IN THE INTESTINE VIA FATTY ACID-BINDING PROTEIN 5 UNCOUPLED WITH THE OBESE PHENOTYPE
(Digestive Disease Week 2024 2024)
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食事由来脂質クオリティが腸管腫瘍リスクに及ぼす影響
(国立高度専門医療研究センター 医療研究連携推進本部 合同リトリート 2024)
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Education (1)：
- 2016 - 2019 日本大学 生物資源科学研究科 応用生命科学専攻 博士後期課程
Professional career (1)：
Work history (6)：
Awards (2)：
- 2023/04 - Japan Health Research Promotion Bureau Chairman's Award
- 2014/09 - The joint Meeting of the XVIII International Symposium on Gnotobiology (XVIII-ISG) and III International Ecological Forum “Environmental and human health” (EcoForum) Marie E Coates Award to BEST POSTER FROM A YOUNG SCIENTIST at XVIII International Symposium on Gnotobiology The commensal bacteria and short chain fatty acids affect to immunoglobulin A production by the immune cells derived from the gut associated lymphoid tissues in small and large intestines
Association Membership(s) (4)：
日本生化学会
, 日本癌学会
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, 日本食品免疫学会
