Kenji Matsuno

マツノケンジ | Kenji Matsuno

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.ns.kogakuin.ac.jp/~wwa1068/

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (3)：創薬化学 , drug discovery , medicinal chemistry

Research theme for competitive and other funds (11)：

2021 - 2024 海洋生物由来新規キヌレニン産生阻害剤のがん免疫寛容抑制剤としての展開
2021 - 2024 LSD阻害剤の創製:LSD1阻害剤の創薬展開およびLSD2機能解明の基盤構築
2020 - 2023 Novel combination immunotherapy for glioma with new Tryptophan metabolizing enzyme inhibitor and Interferon
2018 - 2022 Search for marine organisms-derived compounds that regulate the reprogramming mechanism of cancer cells
2017 - 2020 先例のないフェノタイプを惹起する細胞周期阻害剤の創薬展開と作用機序解明

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Papers (44)：

Hideaki Niwa, Chiduru Watanabe, Shin Sato, Toshiyuki Harada, Hisami Watanabe, Ryo Tabusa, Shunsuke Fukasawa, Ayane Shiobara, Tomoko Hashimoto, Osamu Ohno, et al. Structure-Activity Relationship and In Silico Evaluation of cis- and trans-PCPA-Derived Inhibitors of LSD1 and LSD2. ACS Medicinal Chemistry Letters. 2022. 13. 9. 1485-1492
Miyako Naganuma, Nobumichi Ohoka, Genichiro Tsuji, Haruna Tsujimura, Kenji Matsuno, Takao Inoue, Mikihiko Naito, Yosuke Demizu. Development of Chimeric Molecules That Degrade the Estrogen Receptor Using Decoy Oligonucleotide Ligands. ACS medicinal chemistry letters. 2022. 13. 1. 134-139
Jun-ichi Sawada, Kenji Matsuno, Naohisa Ogo, Akira Asai. Various effects of two types of kinesin-5 inhibitors on mitosis and cell proliferation. Biochemical Pharmacology. 2021. 114789-114789
Miyuki Kumazawa, Manabu Tejima, Miwa Fukuda, Shota Takeda, Kenji Suzuki, Yukiko Mizumoto, Kakeru Sato, Minoru Waki, Hiroyuki Miyachi, Akira Asai, et al. Discovery of Carbono(di)thioates as Indoleamine 2,3-Dioxygenase 1 Inhibitors. ACS medicinal chemistry letters. 2021. 12. 2. 211-216
Genichiro Tsuji, Yosuke Demizu, Miyako Naganuma, Hidetomo Yokoo, Takashi Misawa, Kenji Matsuno. Design and Synthesis of 4-(2-Pyrrolyl)-4-phenylheptane Derivatives as Estrogen Receptor Antagonists. HETEROCYCLES. 2020. 101. 2. 429-429

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MISC (32)：

古内志拓, 人見悠毅, 佐々木智未, 岡本岳大, 辻厳一郎, 黒原崇, 出水庸介, 大野修, 松野研司. Structure determination and total synthetic study on KNP-1, a cyclic depsipeptide that inhibits kynurenine production. 日本薬学会年会要旨集(Web). 2023. 143rd
永沼美弥子, 大岡伸通, 辻村はるな, 松野研司, 内藤幹彦, 井上貴雄, 辻厳一郎, 出水庸介. デコイ核酸をリガンドとしたエストロゲン受容体分解誘導分子の開発. 日本薬学会年会要旨集. 2022. 142年会. 26T-pm04S
古内志拓, 古内志拓, 人見悠毅, 佐々木智未, 岡本岳大, 辻厳一郎, 黒原崇, 出水庸介, 大野修, 松野研司. Structure determination and total synthesis of KNP-1, a cyclic depsipeptide that inhibits kynurenine production. メディシナルケミストリーシンポジウム講演要旨集. 2022. 39th (CD-ROM)
永沼美弥子, 大岡伸通, 辻厳一郎, 松野研司, 内藤幹彦, 井上貴雄, 出水庸介, 出水庸介, 出水庸介. Development of oligonucleotide-based PROTACs. メディシナルケミストリーシンポジウム講演要旨集. 2022. 39th (CD-ROM)
永沼美弥子, 大岡伸通, 辻厳一郎, 松野研司, 内藤幹彦, 井上貴雄, 出水庸介, 出水庸介, 出水庸介. Development of oligonucleotide-based PROTACs. メディシナルケミストリーシンポジウム講演要旨集. 2022. 39th (CD-ROM)

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Patents (25)：

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Professional career (1)：

Awards (2)：

Association Membership(s) (2)：

THE PHARMACEUTICAL SOCIETY OF JAPAN , THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY

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