de Araujo Herculano Bruno

デアラウジョエルクラノブルーノ | de Araujo Herculano Bruno

Affiliation and department：
Job title：日本学術振興会特別研究員

Research field (4)： Molecular biochemistry , Neuroscience - general , Molecular biology , Neurology

Research keywords (6)： Multiple Sclerosis , Neurodegeneration , Neurogenesis , Spinal and Bulbar Muscular Atrophy , Alzheimer's Disease , Neuroscience

Research theme for competitive and other funds (1)：

2020 - 2022 Drug screening system for early pathology of SBMA using disease specific iPSCs and novel biomarkers

Papers (14)：

Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs. Molecular Brain. 2020
Vilariño-Güell C, Zimprich A, Martinelli-Boneschi F, Herculano B, Wang Z, Matesanz F, Urcelay E, Vandenbroeck K, Leyva L, Gris D, et al. Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease. PLoS genetics. 2019. 15. 6. e1008180
A Novel Cell-based β-secretase Enzymatic Assay for Alzheimer’s Disease. 2019
Xiulian Sun, Yili Wu, Bruno Herculano, Weihong Song. RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis. PLOS ONE. 2014. 9. 4
Samuel Vandresen-Filho, Wagner C. Martins, Daniela B. Bertoldo, Gianni Mancini, Bruno A. Herculano, Andreza F. de Bem, Carla I. Tasca. Atorvastatin prevents cell damage via modulation of oxidative stress, glutamate uptake and glutamine synthetase activity in hippocampal slices subjected to oxygen/glucose deprivation. NEUROCHEMISTRY INTERNATIONAL. 2013. 62. 7. 948-955

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MISC (4)：

Lectures and oral presentations (8)：

Drug screening for early pathology of SBMA using disease specific iPSCs and novel biomarkers.
(19th Meeting of the Japanese Society for Regenerative Medicine 2020)
Real-time evaluation of BACE1 activity on APP C99 site through a novel cell-based protein reporter.
(12th Annual Canadian Neuroscience Meeting 2018)
Real-time evaluation of BACE1 activity on APP C99 site through a novel cell-based protein reporter.
(Society for Neuroscience Annual Meeting 2017)
Evaluation of the etiology and progression of Alzheimer’s Disease utilizing Transgenic mice fed with a High Fat Diet.
(Alzheimer’s Association International Conference 2012)
Evaluation of the etiology and progression of Alzheimers Disease utilizing Transgenic mice fed with a High Fat Diet
(The 34th Annual Meeting of the Japan Neuroscience Society 2011)

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Education (3)：

2013 - 2019 University of British Columbia Psychiatry Ph.D. Neuroscience
2009 - 2011 The University of Tokyo Graduate School of Frontier Sciences M.Sc. Integrated Biosciences
2004 - 2009 Universidade Federal de Santa Catarina Biological Sciences B.Sc. Biological Sciences

Professional career (1)：

PhD (University of British Columbia)

Work history (6)：

2020/01 - 現在 Aichi Medical University Neurology JSPS Postdoctoral Fellow
2019/10 - 2019/12 Aichi Medical University Department of Neurology Project Assistant Professor
2019/08 - 2019/09 Aichi Medical University Department of Neurology Researcher
2013/01 - 2019/04 University of British Columbia Department of Psychiatry Doctoral Fellow
2009/04 - 2012/09 The University of Tokyo Graduate School of Frontier Sciences Government Scholar

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Awards (6)：

2020/01 - Japanese Society for the Promotion of Science JSPS Postdoctoral Fellowship for Research in Japan (Short-term)
2018/01 - University of British Columbia Faculty of Medicine Graduate Award
2013/01 - University of British Columbia 4YF Doctoral Fellowship
2012/04 - The University of Tokyo - Graduate School of Frontier Sciences - Integrated Biosciences Outstanding Master's Thesis Award
2009/04 - Monbukagasho Research Scholarship

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