2019 - 2020 Development of a novel method for hydroxytyrosol production by high-performance platform strain for aromatic compounds production
2015 - 2020 Development of a new method for chromosome-editting which is applicable to broad-ragne of bacteria
2009 - 2011 Generation of codon-synchronized Escherichia coli for expression of heterologous genes
2007 - 2009 Fermentative production of aromatic compounds for biorefinery
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Papers (28):
Ning Shen, Yasuharu Satoh, Daisuke Koma, Hiroyuki Ohashi, Yasushi Ogasawara, Tohru Dairi. Optimization of tyrosol-producing pathway with tyrosine decarboxylase and tyramine oxidase in high-tyrosine-producing Escherichia coli. Journal of Bioscience and Bioengineering. 2024. 137. 2. 115-123
Hiroyuki Ohashi, Daisuke Koma, Hayato Yamanaka, Takashi Ohmoto. Enzymatic properties of UDP-glycosyltransferase 89B1 from radish and modulation of enzyme catalytic activity via loop region mutation. PLOS One. 2024. 19. 2. e0299755
Yasuharu Satoh, Keita Fukui, Daisuke Koma, Ning Shen, Taek Soon Lee. Engineered Escherichia coli platforms for tyrosine-derivative production from phenylalanine using phenylalanine hydroxylase and tetrahydrobiopterin-regeneration system. Biotechnology for Biofuels and Bioproducts. 2023. 16. 1. 115-115
Daisuke Koma, Makoto Fujisawa, Hiroyuki Ohashi, Hayato Yamanaka, Kunihiko Moriyoshi, Eiji Nagamori, Takashi Ohmoto. Production of 3-Hydroxytyrosol from Glucose by Chromosomally Engineered Escherichia coli by Fed-Batch Cultivation in a Jar Fermenter. Journal of Agricultural and Food Chemistry. 2023. 71. 24. 9451-9459
Takehiro Fujita, Eri Nishi, Daisuke Koma, Masanobu Naito. Hydroxytyrosol: Bioinspired Nature-Based Adhesive Motif with Excellent Chemical Modifiability and Stability. ACS Applied Polymer Materials. 2023. 5. 5. 3230-3234
2016/05 - Osaka Industrial Research Association Industrial Technology Awards ponsored by Osaka Industrial Research Association Production of aromatic chemicals by metabolically engineered Escherichia coli
Association Membership(s) (4):
American Society for Microbiology
, Japan Society for Environmental Biotechnology
, Japan Society for Bioscience, Biotechnology, and Agrochemistry
, The Society for Biotechnology, Japan