Rchr
J-GLOBAL ID:201901018914499668   Update date: Apr. 01, 2024

Otsuka Yuichi

オオツカ ユウイチ | Otsuka Yuichi
Affiliation and department:
Job title: Associate Professor
Research field  (3): Bacteriology ,  Molecular biology ,  Applied microbiology
Research keywords  (7): antimicrobial resistance ,  gene expression ,  horizontal gene transfer ,  toxin-antitoxin system ,  bacteria ,  bacteriophage ,  ファージセラピー
Research theme for competitive and other funds  (7):
  • 2020 - 2023 The toxin-antitoxin systems suppress the expansion of antimicrobial resistant bacteria
  • 2017 - 2021 Repression of the spread of antimicrobial resistant bacteria and pathogenic bacteria using the bacterial toxin-antitoxin system
  • 2013 - 2017 The functional analysis and the application of bacterial toxin-antitoxin system
  • 2011 - 2015 Inspection of mechanism for recognition of host by phage
  • 2009 - 2010 Relationship of cytoplasmic capping to translation and cell stress
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Papers (27):
  • Takaomi Sasaki, Saya Takita, Takashi Fujishiro, Yunosuke Shintani, Satoki Nojiri, Ryota Yasui, Tetsuro Yonesaki, Yuichi Otsuka. Phage single-stranded DNA-binding protein or host DNA damage triggers the activation of the AbpAB phage defense system. mSphere. 2023. 8. 6. e0037223
  • Kosuke Takada, Kotone Hama, Takaomi Sasaki, Yuichi Otsuka. The hokW-sokW Locus Encodes a Type I Toxin-Antitoxin System That Facilitates the Release of Lysogenic Sp5 Phage in Enterohemorrhagic Escherichia coli O157. Toxins. 2021. 13. 11. 796-796
  • Akiyo Suga, Marina Kawaguchi, Tetsuro Yonesaki, Yuichi Otsuka. Manipulating Interactions between T4 Phage Long Tail Fibers and Escherichia coli Receptors. Applied and Environmental Microbiology. 2021. 87. 13
  • Otsuka Y, Ishikawa T, Takahashi C, Masuda M. A short peptide derived from the ZorO toxin functions as an effective antimicrobial. Toxins. 2019. 11. 7. DOI:10.3390/toxins11070392
  • Kenta Naka, Dan Qi, Tetsuro Yonesaki, Yuichi Otsuka. RnlB Antitoxin of the Escherichia coli RnlA-RnlB Toxin-Antitoxin Module Requires RNase HI for Inhibition of RnlA Toxin Activity. TOXINS. 2017. 9. 1. DOI:10.3390/toxins9010029
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Books (1):
  • RNA Damage and Repair
    Kotta-Loizou Ioly・Springer 2021 ISBN:9783030765712
Lectures and oral presentations  (8):
  • The arms race between bacteria and phages ~toxin-antitoxin systems~
    (2018)
  • この世はウイルスだらけ
    (日本微生物学連盟フォーラム「微生物:変わり者たちの素顔」 2017)
  • 細菌とファージの生存戦略:トキシン-アンチトキシン系の制御
    (第39回日本分子生物学会年会 2016)
  • 細菌のトキシン-アンチトキシン系とファージ感染との関係
    (第89回日本細菌学会総会 2016)
  • ファージ療法・T4ファージを用いた新しいチャレンジ
    (日本農芸化学会西日本支部大会シンポジウム 2014)
more...
Education (3):
  • 2000 - 2003 Osaka University
  • 1998 - 2000 Osaka University
  • 1994 - 1998 Osaka University
Professional career (1):
  • 博士(理学) (大阪大学)
Work history (4):
  • 2018/04 - 現在 Saitama University
  • 2014/04 - 2018/03 Dokkyo Medical University
  • 2009/04 - 2014/03 Osaka University
  • 2004/03 - 2009/03 The Ohio State University
Association Membership(s) (4):
日本ファージセラピー研究会 ,  ファージ研究会 ,  JAPANESE SOCIETY FOR BACTERIOLOGY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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