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J-GLOBAL ID：201802276274266408   Reference number：18A1345987

RnlB Antitoxin of the Escherichia coli RnlA-RnlB Toxin-Antitoxin Module Requires RNase HI for Inhibition of RnlA Toxin Activity

大腸菌RnlA-RnlB毒素-抗毒素モジュールのRnlB抗毒素はRnlA毒素活性の阻害のためにRNアーゼHIを必要とする【JST・京大機械翻訳】

Author (4)： Naka Kenta (Department of Biological Sciences, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan) ,  Qi Dan (Department of Biological Sciences, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan) ,  Yonesaki Tetsuro (Department of Biological Sciences, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan) ,  Otsuka Yuichi (Department of Microbiology, School of Medicine, Dokkyo Medical University, 880 Kitakobayashi, Mibu-machi, Shimotsuga-gun, Tochigi 321-0293, Japan)
Material： Toxins (Web)
Volume： 9  Issue： 1  Page： 29  Publication year： 2017 
JST Material Number： U7286A  ISSN： 2072-6651  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The Escherichia coli RnlA-RnlB...

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Thesaurus term： interaction ,  *Escherichia coli ,  toxicity ,  mRNA ,  *toxin ,  Bacteriophages ,  *antitoxin ,  infection ,  Cell Proliferation ,  DNA Replication ,  Tequatrovirus T4 ,  wild type ,  Endoribonucleases ,  endogenous ,  domain structure ,  *microorganism ,  T-phage

Author keywords (5)： toxin-antitoxin system ,  RnlA-RnlB ,  RNase HI ,  Escherichia coli ,  bacteriophage

JST classification (2)： Enzyme in general  (EB09010D) ,  Microorganism biochemistry  (EG03020N)

Reference (43)：

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• Yamaguchi, Y.; Inouye, M. mRNA interferases, sequence-specific endoribonucleases from the toxin-antitoxin systems. Prog. Mol. Biol. Transl. Sci. 2009, 85, 467-500.
• Zhang, Y.; Inouye, M. RatA (YfjG), an Escherichia coli toxin, inhibits 70S ribosome association to block translation initiation. Mol. Microbiol. 2011, 79, 1418-1429.
• Mutschler, H.; Gebhardt, M.; Shoeman, R.L.; Meinhart, A. A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis. PLoS Biol. 2011, 9, e1001033.

Terms in the title (7)： 大腸菌 ,  毒素 ,  抗毒素 ,  モジュール ,  活性 ,  阻害 ,  RNアーゼHI