Rchr
J-GLOBAL ID:201901019650185488   Update date: Jun. 12, 2024

Motohashi Norio

モトハシ ノリオ | Motohashi Norio
Affiliation and department:
Other affiliations (1):
Research field  (7): Clinical pharmacy ,  Physiology ,  Cell biology ,  Molecular biology ,  Laboratory animal science ,  Nutrition and health science ,  Sports science
Research keywords  (6): サルコペニア ,  筋ジストロフィー ,  Muscle metabolism ,  Muscle fiber type ,  Muscle stem cell ,  Skeletal muscle
Research theme for competitive and other funds  (9):
  • 2021 - 2026 Multi-omics technologies to reveal common mechanism of dystrophic and sarcopenic skeletal muscles
  • 2021 - 2024 Clarification of the mechanisms of muscle atrophy by RNA-binding proteins
  • 2019 - 2022 Elucidation of pathogenesis of sarcopenia based on the plasticity of metabolism of skeletal muscle
  • 2018 - 2021 Elucidation of the mechanisms of age-related muscle atrophy and development of novel therapies for sarcopenia
  • 2016 - 2019 Elucidation of pathogenesis of sarcopenia based on the mechanism of metabolic changes of skeletal muscle
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Papers (50):
  • Ryo Shiraishi, Gabriele Cancila, Kohei Kumegawa, Jacob Torrejon, Irene Basili, Flavia Bernardi, Patricia Benites Goncalves da Silva, Wanchen Wang, Owen Chapman, Liying Yang, et al. Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression. Developmental cell. 2024
  • Katsuhiko Kunitake, Norio Motohashi, Takafumi Inoue, Yutaka Suzuki, Yoshitsugu Aoki. Characterization of CD90/Thy-1 as a crucial molecular signature for myogenic differentiation in human urine-derived cells through single-cell RNA sequencing. Scientific reports. 2024. 14. 1. 2329-2329
  • Norio Motohashi, Katsura Minegishi, Yoshitsugu Aoki. Inherited myogenic abilities in muscle precursor cells defined by the mitochondrial complex I-encoding protein. Cell death & disease. 2023. 14. 10. 689-689
  • Nao Yamauchi, Katsuyuki Tamai, Iori Kimura, Azuma Naito, Nao Tokuda, Yuki Ashida, Norio Motohashi, Yoshitsugu Aoki, Takashi Yamada. High-intensity interval training in the form of isometric contraction improves fatigue resistance in dystrophin-deficient muscle. The Journal of physiology. 2023. 601. 14. 2917-2933
  • Takami Ishizuka, Hirofumi Komaki, Yasuko Asahina, Harumasa Nakamura, Norio Motohashi, Eri Takeshita, Yuko Shimizu-Motohashi, Akihiko Ishiyama, Chihiro Yonee, Shinsuke Maruyama, et al. Systemic administration of the antisense oligonucleotide NS -089/ NCNP -02 for skipping of exon 44 in patients with Duchenne muscular dystrophy: Study protocol for a phase I/ II clinical trial. Neuropsychopharmacology Reports. 2023. 43. 2. 277-286
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MISC (59):
  • 本橋 紀夫, Saifullah Saifullah, 芦田 雪, 青木 吉嗣. 筋代謝制御による筋ジストロフィーの新しい治療戦略. 日本筋学会学術集会・筋ジストロフィー医療研究会合同学術集会プログラム・抄録集. 2023. 9回・10回. 61-61
  • William Valentine, 本橋 紀夫, 柳田 圭介, 徳岡 涼美, 北 芳博, 清水 孝雄, 進藤 英雄, 青木 吉嗣. LPLAT13/MBOAT2はジストロフィー骨格筋のリン脂質を制御し、効率的な再生に必要. 日本筋学会学術集会・筋ジストロフィー医療研究会合同学術集会プログラム・抄録集. 2023. 9回・10回. 78-78
  • 芦田 雪, 本橋 紀夫, 青木 吉嗣. マイオスタチン発現抑制と筋収縮トレーニングの併用による骨格筋萎縮治療. 日本筋学会学術集会・筋ジストロフィー医療研究会合同学術集会プログラム・抄録集. 2023. 9回・10回. 82-82
  • 大越 一輝, 邦武 克彦, 本橋 紀夫, 青木 吉嗣. ヒト尿由来細胞から分化させた神経筋接合部モデルの作出の試み. 日本筋学会学術集会・筋ジストロフィー医療研究会合同学術集会プログラム・抄録集. 2023. 9回・10回. 100-100
  • 山内 菜緒, 内藤 雷, 徳田 奈央, 芦田 雪, 本橋 紀夫, 青木 吉嗣, 山田 崇史. 等尺性運動はAMPK活性化を介しジストロフィン欠損筋の病態および持久力を改善する. 日本筋学会学術集会・筋ジストロフィー医療研究会合同学術集会プログラム・抄録集. 2023. 9回・10回. 118-118
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Education (3):
  • 2005 - 2008 Waseda University Graduate School of Human Sciences
  • 2003 - 2005 Waseda University Graduate School of Human Sciences
  • 1999 - 2003 Waseda University School of Human Sciences
Professional career (1):
  • 博士(人間科学) (早稲田大学)
Work history (10):
  • 2020/04 - 現在 National Center of Neurology and Psychiatry National Institute of Neuroscience, Ncnp
  • 2019/08 - 2020/03 National Center of Neurology and Psychiatry National Institute of Neuroscience, Ncnp
  • 2016/04 - 2020/03 Senshu University School of Law
  • 2014/08 - 2019/08 東京都健康長寿医療センター研究所 老年病態研究チーム 研究員
  • 2014/04 - 2014/07 日本学術振興会 海外特別研究員
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Committee career (1):
  • 2012/09 - 現在 日本体力医学会 評議員
Association Membership(s) (4):
Japanese society of Neurological Therapeutics ,  日本分子生物学会 ,  THE JAPANESE SOCIETY OF PHYSICAL FITNESS AND SPORTS MEDICINE ,  THE JAPAN MUSCLE SOCIETY
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