Art

J-GLOBAL ID：201902211323044200   Reference number：19A1531855

Pioglitazone suppresses macrophage proliferation in apolipoprotein-E deficient mice by activating PPARγ

PPARγを活性化することによりアポリポ蛋白質E欠損マウスにおけるマクロファージ増殖を抑制するピoglitazone【JST・京大機械翻訳】

Author (13)： Murakami-Nishida Saiko (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Matsumura Takeshi (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Senokuchi Takafumi (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Ishii Norio (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Kinoshita Hiroyuki (Department of Diabetes and Endocrinology, National Hospital Organization, Kumamoto Medical Center, Kumamoto, Japan) ,  Yamada Sarie (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Morita Yutaro (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Nishida Shuhei (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Motoshima Hiroyuki (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Kondo Tatsuya (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Komohara Yoshihiro (Department of Cell Pathology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Araki Eiichi (Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan) ,  Araki Eiichi (Center for Metabolic Regulation of Healthy Aging (CMHA), Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan)
Material： Atherosclerosis
Volume： 286  Page： 30-39  Publication year： 2019 
JST Material Number： E0599B  ISSN： 0021-9150  CODEN： ATHSBL  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Local macrophage proliferation...

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Thesaurus term： *macrophage ,  siRNA ,  Apoptosis ,  *apo E ,  high fat diet ,  peritoneal macrophage ,  *PPAR gamma ,  in vitro experiment ,  plaque ,  oral administration ,  Atherosclerosis ,  Sinus of Valsalva ,  nitrogen heterocyclic compound ,  sulfur heterocyclic compound ,  lactam ,  phenol ether ,  phenolic compound ,  oxygen heterocyclic compound ,  urea compound ,  polynuclear aromatic compound

Author keywords (4)： Atherosclerosis ,  Macrophage ,  Peroxisome proliferator-activated receptor-γ ,  Thiazolidinedione

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (3)： Thiazolidine ,  Pioglitazone ,  Troglitazone

Terms in the title (7)： PPARγ ,  活性化 ,  アポリポ蛋白質E ,  欠損 ,  マウス ,  マクロファージ ,  増殖