Art

J-GLOBAL ID：201902214609876778   Reference number：19A1052206

Induced expression of GINS complex is an essential step for reactivation of quiescent stem-like tumor cells within the peri-necrotic niche in human glioblastoma

GINS複合体の誘導発現は,ヒト神経膠芽細胞腫における周囲壊死ニッチ内の静止幹様腫瘍細胞の再活性化に不可欠な段階である【JST・京大機械翻訳】

Author (6)： Kimura Tokuhiro (Department of Pathology, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Cui Dan (Department of Pathology, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Kawano Hiroo (Department of Basic Laboratory Sciences, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Yoshitomi-Sakamoto Chihiro (Department of Pathology, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan) ,  Takakura Nobuyuki (Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan) ,  Ikeda Eiji (Department of Pathology, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan)
Material： Journal of Cancer Research and Clinical Oncology
Volume： 145  Issue： 2  Page： 363-371  Publication year： 2019 
JST Material Number： T0032A  ISSN： 0171-5216  CODEN： JCROD  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Glioblastoma is still intracta...

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Thesaurus term： oxygen deficiency ,  *glioblastoma ,  immunohistochemistry ,  tumorigenesis ,  siRNA ,  phenotype ,  *necrosis ,  *human(primates) ,  *tumor cell ,  serum
Semi thesaurus term： 遺伝子ノックダウン法 ,  微小環境 ,  細胞株 ,  *再活性化 ,  *ニッチ , 【Automatic Indexing@JST】

Author keywords (6)： GINS complex ,  Glioblastoma ,  Niche ,  Necrosis ,  Quiescence ,  Proliferation

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumors(=neoplasms)of nervous system  (GN04000V)

Terms in the title (11)： GINS複合体 ,  誘導発現 ,  ヒト ,  神経膠芽細胞腫 ,  壊死 ,  ニッチ ,  静止 ,  幹 ,  腫瘍細胞 ,  再活性化 ,  段階