Art

J-GLOBAL ID：201902218460850592   Reference number：19A1883478

Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR

EGFRの二量化腕構造を模倣した環状ペプチドによるEGFR陽性癌細胞へのプロアポトーシスペプチドの送達【JST・京大機械翻訳】

Author (4)： Toyama Kei (Department of Medicinal Chemistry, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Japan) ,  Nomura Wataru (Department of Medicinal Chemistry, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Japan) ,  Kobayakawa Takuya (Department of Medicinal Chemistry, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Japan) ,  Tamamura Hirokazu (Department of Medicinal Chemistry, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Japan)
Material： Bioconjugate Chemistry  (Bioconj Chem)
Volume： 29  Issue： 6  Page： 2050-2057  Publication year： 2018 
JST Material Number： W0169A  ISSN： 1043-1802  CODEN： BCCHES  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： A cyclic decapeptide, CQTPYYMN...

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Thesaurus term： *dimerization ,  *apoptosis ,  medium ,  therapy ,  *EGF receptor ,  cation ,  peptide bond hydrolase ,  siRNA ,  *tumor cell ,  *peptide ,  *cyclopeptide ,  A549 cell ,  conjugation
Semi thesaurus term： 特異性 ,  *環状 , 【Automatic Indexing@JST】

JST classification (2)： Cell physiology in general  (EF02010S) ,  Proteins and peptides in general  (EB03010N)

Terms in the title (7)： EGFR ,  二量化 ,  腕 ,  模倣 ,  環状ペプチド ,  癌細胞 ,  送達