Art

J-GLOBAL ID：201902219275477257   Reference number：19A0632471

Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging

骨細胞Sema3Aの自己調節はエストロゲン作用を調整し,骨老化を抑制する【JST・京大機械翻訳】

Author (8)： Hayashi Mikihito (Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan) ,  Nakashima Tomoki (Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan) ,  Nakashima Tomoki (Japan Science and Technology Agency (JST), Precursory Research for Embryonic Science and Technology (PRESTO), Tokyo 113-8549, Japan) ,  Nakashima Tomoki (Japan Agency for Medical Research and Development, Core Research for Evolutional Science and Technology (AMED-CREST), Tokyo 113-8549, Japan) ,  Yoshimura Noriko (Department of Joint Disease Research, 22nd Century Medical and Research Center, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Okamoto Kazuo (Department of Osteoimmunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Tanaka Sakae (Department of Orthopedic Surgery, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Takayanagi Hiroshi (Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan)
Material： Cell Metabolism
Volume： 29  Issue： 3  Page： 627-637.e5  Publication year： 2019 
JST Material Number： W3108A  ISSN： 1550-4131  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Osteocyte survival is key to b...

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Thesaurus term： homeostasis ,  osteoblast ,  Phenotype ,  Bone Resorption ,  Ovariectomy ,  osteogenesis ,  osteoporosis ,  secretory protein ,  receptor ,  serum concentration ,  human ,  *senile change ,  *Semaphorin-3A ,  *Osteocytes ,  Signal Transduction
Semi thesaurus term： cellular signal transduction , 【Automatic Indexing@JST】

Author keywords (3)： bone aging ,  Sema3A ,  osteocyte

JST classification (2)： Basic medicine on musculoskeletal system  (GG01020B) ,  Skeletal system  (EJ10030R)

Terms in the title (6)： 骨細胞 ,  Sema3A ,  自己調節 ,  エストロゲン ,  骨 ,  老化