Art

J-GLOBAL ID：201902220187913323   Reference number：19A1110718

A Three-Compartment Pharmacokinetic Model to Predict the Interstitial Concentration of Talaporfin Sodium in the Myocardium for Photodynamic Therapy: A Method Combining Measured Fluorescence and Analysis of the Compartmental Origin of the Fluorescence

光線力学的治療のための心筋におけるTalaporfinナトリウムの間質濃度を予測するための3コンパートメント薬物動態モデル:測定した蛍光と蛍光のコンパートメント起源の分析を組み合わせた方法【JST・京大機械翻訳】

Author (5)： Uno Yuko (School of Fundamental Science and Technology, Graduate School of Science and Technology, Keio University, 3-14-1, Hiyoshi, Kohoku-ku, Yokohama City, Kanagawa 223-8522, Japan) ,  Ogawa Emiyu (School of Allied Health Science, Kitasato University, Kanagawa 252-0373, Japan) ,  Aiyoshi Eitaro (The Institute of Statistical Mathematics, Tokyo 190-0014, Japan) ,  Arai Tsunenori (School of Fundamental Science and Technology, Graduate School of Science and Technology, Keio University, 3-14-1, Hiyoshi, Kohoku-ku, Yokohama City, Kanagawa 223-8522, Japan) ,  Arai Tsunenori (Department of Applied Physics and Physico-Informatics, Faculty of Science and Technology, Keio University, Kanagawa 223-8522, Japan)
Material： Bioengineering (Web)
Volume： 6  Issue： 1  Page： 1  Publication year： 2018 
JST Material Number： U7144A  ISSN： 2306-5354  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： To evaluate the effectiveness ...

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Thesaurus term： *pharmacokinetics ,  differential ,  fin(machine element) ,  plasma concentration ,  rate equation ,  plasma(blood) ,  *fluorescence ,  *sodium ,  *myocardium ,  linearity ,  effectiveness ,  *interstitial tissue
Semi thesaurus term： 決定係数 ,  速度定数 ,  タリン , 【Automatic Indexing@JST】

Author keywords (5)： talaporfin sodium ,  pharmacokinetics ,  three-compartment model ,  interstitial space ,  myocardial fluorescence

JST classification (1)： Gene manipulation  (EC02050B)

Reference (27)：

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• Kimura, T.; Takatsuki, S.; Miyoshi, S.; Takahashi, M.; Ogawa, E.; Nakajima, K.; Kashimura, S.; Katsumata, Y.; Nishiyama, T.; Nishiyama, N.; et al. Electrical superior vena cava isolation using photodynamic therapy in a canine model. Europace 2016, 18, 294-300.
• Kato, H.; Furukawa, K.; Sato, M.; Okunaka, T.; Kusunoki, Y.; Kawahara, M.; Fukuoka, M.; Miyazawa, T.; Yana, T.; Matsui, K.; et al. Phase II clinical study of photodynamic therapy using mono-L-aspartyl chlorin e6 and diode laser for early superficial squamous cell carcinoma of the lung. Lung Cancer 2003, 42, 103-111.

Terms in the title (10)： 光線力学的治療 ,  心筋 ,  ナトリウム ,  間質 ,  予測 ,  コンパートメント ,  薬物動態モデル ,  蛍光 ,  起源 ,  分析