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J-GLOBAL ID：201902221191427064   Reference number：19A2704606

Identification of glycyrrhizin metabolites in humans and of a potential biomarker of liquorice-induced pseudoaldosteronism: a multi-centre cross-sectional study

ヒトにおけるグリチルリチン代謝産物の同定と,カンゾウ誘発偽性アルドステロン症のバイオマーカーの可能性:多施設横断研究【JST・京大機械翻訳】

Author (11)： Takahashi Kanon (Division of Pharmaceutical Care Sciences, Graduate School of Pharmacy, Keio University, Tokyo, Japan) ,  Yoshino Tetsuhiro (Center for Kampo Medicine, Keio University School of Medicine, Tokyo, Japan) ,  Maki Yasuhito (Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Ishiuchi Kan'ichiro (Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Namiki Takao (Department of Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan) ,  Ogawa-Ochiai Keiko (Department of Otorhinolaryngology and Head and Neck Surgery, Clinic of Japanese Oriental (Kampo) Medicine, Kanazawa University Hospital, Kanazawa-City, Ishikawa, Japan) ,  Minamizawa Kiyoshi (Department of Oriental Medicine, Kameda Medical Center, Kamogawa, Chiba, Japan) ,  Makino Toshiaki (Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan) ,  Nakamura Tomonori (Division of Pharmaceutical Care Sciences, Graduate School of Pharmacy, Keio University, Tokyo, Japan) ,  Mimura Masaru (Center for Kampo Medicine, Keio University School of Medicine, Tokyo, Japan) ,  Watanabe Kenji (Center for Kampo Medicine, Keio University School of Medicine, Tokyo, Japan)
Material： Archives of Toxicology
Volume： 93  Issue： 11  Page： 3111-3119  Publication year： 2019 
JST Material Number： D0867A  ISSN： 0340-5761  CODEN： ATXKA8  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Liquorice [main ingredient, gl...

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Thesaurus term： renin ,  *hyperaldosteronism ,  oriental medicine ,  potassium ,  serum ,  *human(primates) ,  side effect ,  *metabolism ,  *Glycyrrhiza uralensis ,  *biomarker ,  *metabolite ,  edema ,  Chinese drug ,  aldehyde ,  steroid ,  enone ,  alicyclic alcohol ,  alicyclic ketone ,  diol ,  diketone ,  hydroxy ketone ,  glycoside(except carbohydrate) ,  pyranoside ,  unsaturated carboxylic acid ,  pentacyclic triterpene

Author keywords (4)： Kampo medicine ,  Side effect ,  Liquorice ,  Glycyrrhizin

JST classification (1)： Toxicity of organic compounds  (GZ02030Y)

Substance index (2)： Aldosterone ,  Glycyrrhizin

Terms in the title (11)： ヒト ,  グリチルリチン ,  代謝産物 ,  同定 ,  カンゾウ ,  誘発 ,  アルドステロン症 ,  バイオマーカー ,  可能性 ,  施設 ,  研究