Art

J-GLOBAL ID：201902221565927584   Reference number：19A1482217

The characterization of AD/PART co-pathology in CJD suggests independent pathogenic mechanisms and no cross-seeding between misfolded Aβ and prion proteins

CJDにおけるAD/部分共病理学の特性化は独立した病原性機構を示唆し,誤折畳みAβとプリオン蛋白質間の交差シーディングを示唆しない【JST・京大機械翻訳】

Author (13)： Rossi Marcello (Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy) ,  Rossi Marcello (IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy) ,  Kai Hideaki (IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy) ,  Kai Hideaki (Department of Neurological Sciences, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Baiardi Simone (Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy) ,  Bartoletti-Stella Anna (IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy) ,  Carla Benedetta (IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy) ,  Zenesini Corrado (IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy) ,  Capellari Sabina (IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy) ,  Capellari Sabina (Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy) ,  Kitamoto Tetsuyuki (Department of Neurological Sciences, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Parchi Piero (Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy) ,  Parchi Piero (IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy)
Material： Acta Neuropathologica Communications (Web)
Volume： 7  Issue： 1  Page： 53  Publication year： 2019 
JST Material Number： U7296A  ISSN： 2051-5960  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Current evidence indicating a ...

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Thesaurus term： Phenotype ,  prion disease ,  Genotype ,  pathogenesis ,  *characterization ,  amyloid beta-protein ,  Heredity ,  *folding (morphology) ,  apo E ,  human ,  *pathological state ,  *Prions ,  *pathogenicity ,  Alzheimer Disease ,  spectrum ,  Amyloid ,  *glycoprotein ,  animal protein ,  *Proteins ,  *prion protein

Author keywords (10)： Creutzfeldt-Jakob disease ,  Prion disease ,  Prion strain ,  Aβ-pathology ,  Tau-pathology ,  CAA ,  PART ,  Neurodegenerative dementia ,  APOE ,  PRNP

JST classification (2)： Nervous system diseases  (GN03000O) ,  Basic neurology  (GN01020W)

Reference (80)：

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Terms in the title (9)： CJD ,  AD ,  病理学 ,  特性化 ,  病原性 ,  折畳み ,  プリオン蛋白質 ,  交差 ,  シーディング