Art

J-GLOBAL ID：201902222350561348   Reference number：19A2626236

In vitro antiviral activity of spirotetronate compounds against dengue virus serotype 2

デングウイルス血清2型に対するスピロテトロン酸化合物のin vitro抗ウイルス活性

Author (15)： Euanorasetr Jirayut (Department of Biotechnology, Faculty of Science, Mahidol University) ,  Euanorasetr Jirayut (Mahidol University-Osaka University: Collaborative Research Center for Bioscience and Biotechnology (MU-OU: CRC), Faculty of Science, Mahidol University) ,  Intra Bungonsiri (Department of Biotechnology, Faculty of Science, Mahidol University) ,  Intra Bungonsiri (Mahidol University-Osaka University: Collaborative Research Center for Bioscience and Biotechnology (MU-OU: CRC), Faculty of Science, Mahidol University) ,  Thunmrongsiri Nutthanit (Department of Biotechnology, Faculty of Science, Mahidol University) ,  Thunmrongsiri Nutthanit (Mahidol University-Osaka University: Collaborative Research Center for Bioscience and Biotechnology (MU-OU: CRC), Faculty of Science, Mahidol University) ,  Limthongkul Jitra (Department of Microbiology, Faculty of Science, Mahidol University) ,  Ubol Sukathida (Department of Microbiology, Faculty of Science, Mahidol University) ,  Anuegoonpipat Atchareeya (Department of Medical Science, National Institute of Health, Ministry of Public Health) ,  Kurosu Takeshi (Department of Virology, Research Institute for Microbial Diseases, Osaka University) ,  Kurosu Takeshi (Department of Virology, National Institute of Infectious Diseases) ,  Ikuta Kazuyoshi (Department of Virology, Research Institute for Microbial Diseases, Osaka University) ,  Nihira Takuya (Mahidol University-Osaka University: Collaborative Research Center for Bioscience and Biotechnology (MU-OU: CRC), Faculty of Science, Mahidol University) ,  Panbangred Watanalai (Department of Biotechnology, Faculty of Science, Mahidol University) ,  Panbangred Watanalai (Mahidol University-Osaka University: Collaborative Research Center for Bioscience and Biotechnology (MU-OU: CRC), Faculty of Science, Mahidol University)
Material： Journal of General and Applied Microbiology  (J Gen Appl Microbiol)
Volume： 65  Issue： 4  Page： 197-203(J-STAGE)  Publication year： 2019 
JST Material Number： G0463A  ISSN： 0022-1260  CODEN： JGAMA9  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antiviral action ,...
Semi thesaurus term： Actinomadura ,...

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Author keywords (5)： Actinomadura ,  antiviral ,  dengue virus ,  NS2B-NS3 protease ,  spirotetronate

JST classification (3)： Virus biochemistry  (EG04030F) ,  Biological function  (EB02020R) ,  Basic research of antiviral drugs  (GW17040O)

Substance index (3)： 2EPS-A ,  2EPS-B ,  2EPS-C

Reference (32)：

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• Bhatt, S., Gething, P. W., Brady, O. J., Messina, J. P., Farlow, A. W. et al. (2013) The global distribution and burden of dengue. Nature, 496, 504-507.
• Bollati, M., Alvarez, K., Assenberg, R., Baronti, C., Canard, B. et al. (2010) Structure and functionality in flavivirus NS-proteins: Perspectives for drug design. Antiviral Res., 87, 125-148.
• Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
• Chappell, K. J., Stoermer, M. J., Fairlie, D. P., and Young, P. R. (2008) West nile virus NS2B/NS3 protease as an antiviral target. Curr. Med. Chem., 15, 2771-2784.

Terms in the title (4)： デングウイルス ,  血清 ,  酸 ,  抗ウイルス活性