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J-GLOBAL ID：201902223567947048   Reference number：19A0243809

Novel Nonsteroidal Progesterone Receptor (PR) Antagonists with a Phenanthridinone Skeleton

フェナントリジノン骨格を有する新規非ステロイド性プロゲステロン受容体(PR)アンタゴニスト【JST・京大機械翻訳】

Author (7)： Nishiyama Yuko (Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan) ,  Mori Shuichi (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan) ,  Makishima Makoto (Nihon University School of Medicine, Tokyo, Japan) ,  Fujii Shinya (Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan) ,  Kagechika Hiroyuki (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan) ,  Hashimoto Yuichi (Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan) ,  Ishikawa Minoru (Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo, Japan)
Material： ACS Medicinal Chemistry Letters
Volume： 9  Issue： 7  Page： 641-645  Publication year： 2018 
JST Material Number： W5043A  ISSN： 1948-5875  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The progesterone receptor (PR)...

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Thesaurus term： contraceptive agent ,  hormone ,  Central Nervous System ,  antagonism ,  Structure-Activity Relationship ,  abortion ,  *progesterone receptor ,  Endometriosis ,  nuclear receptor ,  abnormal labor
Semi thesaurus term： *アンタゴニスト , 【Automatic Indexing@JST】

Author keywords (4)： Progesterone receptor ,  antagonist ,  nonsteroid ,  phenanthridinone

JST classification (2)： Basic research of drugs acting on endocrine system and reproductive organ  (GW10010K) ,  Sex hormones  (EB08050O)

Terms in the title (5)： 骨格 ,  ステロイド ,  プロゲステロン受容体 ,  Pr ,  アンタゴニスト