Art

J-GLOBAL ID：201902225926914829   Reference number：19A0253635

Development of High-Functionality and -Quality Lipids with RGD Peptide Ligands: Application for PEGylated Liposomes and Analysis of Intratumoral Distribution in a Murine Colon Cancer Model

RGDペプチド配位子を有する高機能性および高品質脂質の開発:PEG化リポソームへの応用とマウスColon癌モデルにおける腫瘍内分布の分析【JST・京大機械翻訳】

Author (9)： Suga Tadaharu (Department of Pharmaceutical Informatics, Graduate School of Biomedical Sciences, Nagasaki University, Japan) ,  Suga Tadaharu (Department of Analytical Chemistry for Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, Japan) ,  Kato Naoya (Department of Pharmaceutical Informatics, Graduate School of Biomedical Sciences, Nagasaki University, Japan) ,  Hagimori Masayori (Department of Pharmaceutical Informatics, Graduate School of Biomedical Sciences, Nagasaki University, Japan) ,  Fuchigami Yuki (Department of Pharmaceutical Informatics, Graduate School of Biomedical Sciences, Nagasaki University, Japan) ,  Kuroda Naotaka (Department of Analytical Chemistry for Pharmaceutics, Graduate School of Biomedical Sciences, Nagasaki University, Japan) ,  Kodama Yukinobu (Department of Hospital Pharmacy, Nagasaki University Hospital, Japan) ,  Sasaki Hitoshi (Department of Hospital Pharmacy, Nagasaki University Hospital, Japan) ,  Kawakami Shigeru (Department of Pharmaceutical Informatics, Graduate School of Biomedical Sciences, Nagasaki University, Japan)
Material： Molecular Pharmaceutics
Volume： 15  Issue： 10  Page： 4481-4490  Publication year： 2018 
JST Material Number： W3686A  ISSN： 1543-8384  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： High-functionality and -qualit...

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Thesaurus term： in vitro experiment ,  *tumor ,  *mouse(animal) ,  *liposome ,  polyethylene oxide ,  colonic neoplasm ,  *lipid ,  molecular weight ,  spacer ,  image processing ,  targeting ,  integrin ,  *peptide
Semi thesaurus term： 腫瘍組織 ,  *RGDペプチド , 【Automatic Indexing@JST】

Author keywords (5)： targeted liposomal delivery ,  polyethylene glycol ,  peptide-mediated targeting ,  integrin receptor ,  tissue clearing

JST classification (3)： Physicochemical pharmacy in general  (GV01010J) ,  Biochemistry of lipids in general  (EB05010B) ,  Structure and morphology of polymer solids  (CG02022M)

Terms in the title (14)： RGDペプチド ,  配位子 ,  高品質 ,  脂質 ,  開発 ,  PEG化 ,  リポソーム ,  応用 ,  マウス ,  癌 ,  モデル ,  腫瘍 ,  分布 ,  分析