Art

J-GLOBAL ID：201902230646946140   Reference number：19A2817446

Quantification of ENT1 and ENT2 Proteins at the Placental Barrier and Contribution of These Transporters to Ribavirin Uptake

胎盤関門におけるENT1及びENT2蛋白質の定量化及びこれらの輸送体のリバビリン取り込みへの寄与【JST・京大機械翻訳】

Author (14)： Nishimura Tomohiro (Division of Pharmaceutics, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan) ,  Sano Yuichiro (Division of Pharmaceutics, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan) ,  Takahashi Yu (Division of Pharmaceutics, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan) ,  Noguchi Saki (Division of Pharmaceutics, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan) ,  Uchida Yasuo (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8577, Japan) ,  Takagi Akinori (Division of Pharmaceutics, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan) ,  Takagi Akinori (Laboratory of Applied Therapeutics, Center for Education and Research on Clinical Pharmacy, Showa Pharmaceutical University, Machida, Tokyo 194-8543, Japan) ,  Tanaka Takahiro (Division of Pharmaceutics, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan) ,  Katakura Satomi (Department of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Nakashima Emi (Division of Pharmaceutics, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan) ,  Tachikawa Masanori (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8577, Japan) ,  Maruyama Tetsuo (Department of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Terasaki Tetsuya (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8577, Japan) ,  Tomi Masatoshi (Division of Pharmaceutics, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo 105-8512, Japan)
Material： Journal of Pharmaceutical Sciences  (J Pharm Sci)
Volume： 108  Issue： 12  Page： 3917-3922  Publication year： 2019 
JST Material Number： C0260B  ISSN： 0022-3549  CODEN： JPMSAE  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The aims of this study are to ...

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Thesaurus term： rat ,  *protein ,  fetus ,  human(primates) ,  ovocyte ,  chorion ,  *placental barrier ,  pregnancy ,  trophoblast ,  *placenta ,  amine ,  nitrogen heterocyclic compound ,  aminoalcohol ,  ribonucleoside ,  carboxamide
Semi thesaurus term： ヌクレオシド輸送体 ,  *輸送体 ,  *平衡型ヌクレオシド輸送体1 , 【Automatic Indexing@JST】

Author keywords (6)： drug transport ,  membrane transporter(s) ,  nucleoside transporter ,  pharmacokinetics ,  placenta ,  pregnancy

JST classification (1)： Basic biopharmacy  (GY01021U)

Substance index (2)： Dipyridamole ,  Ribavirin

Terms in the title (7)： 胎盤関門 ,  ENT1 ,  蛋白質 ,  定量化 ,  輸送体 ,  リバビリン ,  取り込み