Art

J-GLOBAL ID：201902233229290411   Reference number：19A2753134

Understanding the Molecular Mechanism Underlying the High Catalytic Activity of p-Hydroxybenzoate Hydroxylase Mutants for Producing Gallic Acid

没食子酸生産のためのp-ヒドロキシ安息香酸ヒドロキシラーゼ変異体の高い触媒活性の基礎となる分子機構の理解【JST・京大機械翻訳】

Author (21)： Moriwaki Yoshitaka (Department of Biotechnology, The University of Tokyo) ,  Moriwaki Yoshitaka (The Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Japan) ,  Yato Mirai (Department of Biotechnology, The University of Tokyo) ,  Terada Tohru (The Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Japan) ,  Terada Tohru (Agricultural Bioinformatics Research Unit, Graduate School of Agricultural and Life Sciences, The University of Tokyo) ,  Saito Seiji (Department of Medical Management and Informatics, Hokkaido Information University, Japan) ,  Saito Seiji (Genaris, Inc., Kanagawa, Japan) ,  Nukui Noriyuki (Genaris, Inc., Kanagawa, Japan) ,  Iwasaki Takumi (Genaris, Inc., Kanagawa, Japan) ,  Nishi Tatsunari (Genaris, Inc., Kanagawa, Japan) ,  Kawaguchi Yuko (Department of Biochemistry and Molecular Biology, Nippon Medical School, Japan) ,  Okamoto Ken (Department of Biochemistry and Molecular Biology, Nippon Medical School, Japan) ,  Okamoto Ken (Department of Applied Biological Chemistry, The University of Tokyo) ,  Arakawa Takatoshi (Department of Biotechnology, The University of Tokyo) ,  Arakawa Takatoshi (The Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Japan) ,  Yamada Chihaya (Department of Biotechnology, The University of Tokyo) ,  Yamada Chihaya (The Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Japan) ,  Fushinobu Shinya (Department of Biotechnology, The University of Tokyo) ,  Fushinobu Shinya (The Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Japan) ,  Shimizu Kentaro (Department of Biotechnology, The University of Tokyo) ,  Shimizu Kentaro (The Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Japan)
Material： Biochemistry
Volume： 58  Issue： 45  Page： 4543-4558  Publication year： 2019 
JST Material Number： B0270B  ISSN： 0006-2960  CODEN： BICHAW  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： p-Hydroxybenzoate hydroxylase ...

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Thesaurus term： hydroxylation ,  crystal structure ,  deprotonation ,  peroxide(inorganic) ,  *catalyst ,  complex(compound) ,  monooxygenase ,  intramolecular dynamics ,  phosphoric acid ,  *catalytic activity ,  mutation ,  aromatic carboxylic acid ,  polyphenol ,  hydroxy acid
Semi thesaurus term： 分子動力学シミュレーション ,  *分子機構 ,  *ヒドロキシ安息香酸ヒドロキシラーゼ , 【Automatic Indexing@JST】

JST classification (1)： Enzyme in general  (EB09010D)

Substance index (1)： Gallic Acid

Terms in the title (8)： 没食子酸 ,  p-ヒドロキシ安息香酸 ,  ヒドロキシラーゼ ,  変異体 ,  触媒活性 ,  基礎 ,  分子 ,  理解