Art

J-GLOBAL ID：201902238484154420   Reference number：19A2170082

Pharmaceutical Inhaled Particle Design by Acoustically Mixing System Based on Vibrational Spectroscopy and Chemometrics

分光学・計量化学的手法に基づく音響混合技術を用いた吸入粉末剤の粒子設計

Author (2)： TANAKA RYOUMA (武蔵野大学大学院薬科学研究科) ,  OTSUKA MAKOTO (武蔵野大学大学院薬科学研究科)
Material： ホソカワ粉体工学振興財団年報(Web)  (Hosokawa Powder Technology Foundation Annual Report (Web))
Volume： 26  Page： 175-179(J-STAGE)  Publication year： 2018 
JST Material Number： U0189A  ISSN： 2189-4663  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *aerosol(pharmaceuticals) ,...

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JST classification (2)： Aerosols  (GY02060C) ,  Production and handling of solid in general  (XD03021O)

Substance index (2)： Theophylline ,  Lactose

Reference (16)：

• Asachi M., Nourafkan E., Hassanpour A., A review of current techniques for the evaluation of powder mixing, Advanced Powder Technology, 29 (2018) 1525-1549. DOI: 10.1016/j.apt.2018.03.031
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• Steckel H., Müller B.W., In vitro evaluation of dry powder inhalers II: influence of carrier particle size and concentration on in vitro deposition, International Journal of Pharmaceutics, 154 (1997) 31-37. DOI: 10.1016/S0378-5173(97)00115-4
• Takahashi N., Nakamura Y., Otsuka M., Tanaka R., Powder inhalant, inhaler and method for producing powder inhalant, JP Patent, (2017) PCT/JP2016/077132, WO2017/047650.
• Tanaka R., Takahashi N., Nakamura Y., Hattori Y., Ashizawa K., Otsuka M., In-line and real-time monitoring of resonant acoustic mixing by near-Infrared spectroscopy combined with chemometric technology for process analytical technology applications in pharmaceutical powder blending systems. Analytical Sciences, 33 (2017) 41-46. DOI: 10.2116/analsci.33.41

Terms in the title (7)： 分光学 ,  計量化学 ,  手法 ,  音響 ,  吸入 ,  粉末剤 ,  粒子設計