Art

J-GLOBAL ID：201902241791271986   Reference number：19A0324888

A Novel Method to Estimate Long-Term Chronological Changes From Fragmented Observations in Disease Progression

疾患進行における断片化観察からの長期経時変化を推定する新しい方法【JST・京大機械翻訳】

Author (11)： Ishida Takaaki (Department of Pharmacy, Faculty of Medicine, The University of Tokyo Hospital, The University of Tokyo, Tokyo, Japan) ,  Tokuda Keita (Department of Pharmacy, Faculty of Medicine, The University of Tokyo Hospital, The University of Tokyo, Tokyo, Japan) ,  Hisaka Akihiro (Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan) ,  Honma Masashi (Department of Pharmacy, Faculty of Medicine, The University of Tokyo Hospital, The University of Tokyo, Tokyo, Japan) ,  Kijima Shinichi (Advanced Review With Electronic Data Promotion Group, Pharmaceuticals and Medical Devices Agency, Tokyo, Japan) ,  Takatoku Hiroyuki (Office of New Drug II, Pharmaceuticals and Medical Devices Agency, Tokyo, Japan) ,  Iwatsubo Takeshi (Department of Neuropathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Moritoyo Takashi (Office of New Drug II, Pharmaceuticals and Medical Devices Agency, Tokyo, Japan) ,  Moritoyo Takashi (Department of Clinical Research Governance, Faculty of Medicine, The University of Tokyo Hospital, The University of Tokyo, Tokyo, Japan) ,  Suzuki Hiroshi (Department of Pharmacy, Faculty of Medicine, The University of Tokyo Hospital, The University of Tokyo, Tokyo, Japan) ,  The Alzheimer's Disease Neuroimaging Initiative
Material： Clinical Pharmacology & Therapeutics  (Clin Pharmacol Ther)
Volume： 105  Issue： 2  Page： 436-447  Publication year： 2019 
JST Material Number： A0721B  ISSN： 0009-9236  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Clinical observations of patie...

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Thesaurus term： *time course ,  apo E ,  clinical trial ,  Alzheimer Disease ,  man ,  amyloid beta-protein ,  woman ,  human ,  reconstitution ,  Homozygote ,  Research Subjects ,  Chronic Disease ,  *Disease Progression ,  Amyloid ,  glycoprotein ,  animal protein
Semi thesaurus term： 共変量 ,  NONMEM ,  病期 , 【Automatic Indexing@JST】

JST classification (3)： Nervous system diseases  (GN03000O) ,  Structure and chemistry of genes  (EC02020U) ,  Biological function  (EB03040U)

Terms in the title (5)： 疾患進行 ,  観察 ,  長期 ,  経時変化 ,  推定