Art

J-GLOBAL ID：201902248913097481   Reference number：19A1972131

Dimeric C34 Derivatives Linked through Disulfide Bridges as New HIV-1 Fusion Inhibitors

新規HIV-1融合阻害剤としてジスルフィド架橋を介して結合した二量体C34誘導体【JST・京大機械翻訳】

Author (8)： Kobayakawa Takuya (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo, 101-0062, Japan) ,  Ebihara Kento (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo, 101-0062, Japan) ,  Honda Yuzuna (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo, 101-0062, Japan) ,  Fujino Masayuki (AIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan) ,  Nomura Wataru (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo, 101-0062, Japan) ,  Yamamoto Naoki (Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore) ,  Murakami Tsutomu (AIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan) ,  Tamamura Hirokazu (Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo, 101-0062, Japan)
Material： ChemBioChem
Volume： 20  Issue： 16  Page： 2101-2108  Publication year： 2019 
JST Material Number： W1258A  ISSN： 1439-4227  CODEN： CBCHFX  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： C34, a 34-mer fragment peptide...

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Thesaurus term： *dimer ,  *HIV ,  monomer ,  *HIV1 ,  *disulfide ,  dimerization ,  pharmacophore ,  linker ,  polyethylene glycolylation ,  C-terminal side ,  HIV Envelope Protein gp41 ,  *disulfide bridge ,  Anti-HIV activity ,  *microorganism ,  *animal virus
Semi thesaurus term： 抗HIV-1作用 ,  抗HIV活性 ,  *HIV融合阻害剤 , 【Automatic Indexing@JST】

Author keywords (5)： antiviral agents ,  C-terminal heptad repeats ,  dimerization ,  disulfide bridges ,  HIV-1 fusion inhibitor

JST classification (2)： Enzyme in general  (EB09010D) ,  Molecular structure  (EB03020Y)

Terms in the title (5)： HIV-1 ,  融合阻害剤 ,  ジスルフィド架橋 ,  二量体 ,  誘導体