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J-GLOBAL ID：201902251397091782   Reference number：19A2821717

Knockdown of DEAD-box RNA helicase DDX5 selectively attenuates serine 311 phosphorylation of NF-κB p65 subunit and expression level of anti-apoptotic factor Bcl-2

DEADボックスRNAヘリカーゼDDX5のノックダウンは,NF-κB p65サブユニットのセリン311リン酸化を選択的に減弱し,抗アポトーシス因子Bcl-2の発現レベルを低下させる【JST・京大機械翻訳】

Author (10)： Tanaka Ken (Department of Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Tanaka Ken (Department of Orthopaedic Surgery, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Tanaka Toshiaki (Department of Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Nakano Tomoyuki (Department of Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Hozumi Yasukazu (Department of Cell Biology and Morphology, Akita University Graduate School of Medicine, Akita 010-8543, Japan) ,  Yanagida Mitsuaki (Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu 279-0021, Japan) ,  Araki Yoshihiko (Institute for Environmental and Gender-specific Medicine, Juntendo University Graduate School of Medicine, Urayasu 279-0021, Japan) ,  Iwazaki Kiyoshi (Department of Orthopaedic Surgery, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Takagi Michiaki (Department of Orthopaedic Surgery, Yamagata University School of Medicine, Yamagata 990-9585, Japan) ,  Goto Kaoru (Department of Anatomy and Cell Biology, Yamagata University School of Medicine, Yamagata 990-9585, Japan)
Material： Cellular Signalling  (Cell Signal)
Volume： 65  Page： Null  Publication year： 2020 
JST Material Number： T0667A  ISSN： 0898-6568  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： NF-κB plays a key role in the ...

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Thesaurus term： gene ,  *subunit ,  TNF alpha ,  phosphatidic acid ,  inflammation ,  down-regulation ,  robustness ,  cell proliferation ,  *NF-kappaB ,  diglyceride ,  translocation(genetics) ,  interaction ,  carcinogenesis ,  *phosphorylation ,  luciferase

Author keywords (5)： DDX5 ,  DEAD-box RNA helicase ,  DGKζ ,  NF-κB ,  Bcl-2

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (11)： DEADボックスRNAヘリカーゼ ,  ノックダウン ,  NF-κB ,  p65 ,  サブユニット ,  リン酸化 ,  減弱 ,  抗アポトーシス ,  因子 ,  BCL-2 ,  発現