Art

J-GLOBAL ID：201902252296305133   Reference number：19A1311323

Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics

複雑な脳回路動力学のin vivoイメージングのための多色geciスイート,XCAMPの合理的エンジニアリング【JST・京大機械翻訳】

Author (36)： Inoue Masatoshi (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Inoue Masatoshi (Department of Bioengineering, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Takeuchi Atsuya (Department of Neurophysiology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Manita Satoshi (Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi 409-3898, Japan) ,  Horigane Shin-ichiro (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Horigane Shin-ichiro (Department of Neuroscience I, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Aichi 464-8601, Japan) ,  Horigane Shin-ichiro (Department of Molecular/Cellular Neuroscience, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan) ,  Sakamoto Masayuki (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Kawakami Ryosuke (Laboratory of Molecular and Cellular Biophysics, Research Institute for Electronic Science, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan) ,  Kawakami Ryosuke (Department of Molecular Medicine for Pathogenesis, Ehime University Graduate School of Medicine, Toon, Ehime 791-0295, Japan) ,  Yamaguchi Kazushi (Laboratory of Molecular and Cellular Biophysics, Research Institute for Electronic Science, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan) ,  Otomo Kouhei (Laboratory of Molecular and Cellular Biophysics, Research Institute for Electronic Science, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan) ,  Yokoyama Hiroyuki (New Industry Creation Hatchery Center (NICHe), Tohoku University, Sendai, Miyagi 980-8579, Japan) ,  Kim Ryang (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Yokoyama Tatsushi (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Takemoto-Kimura Sayaka (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Takemoto-Kimura Sayaka (Department of Neuroscience I, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Aichi 464-8601, Japan) ,  Takemoto-Kimura Sayaka (Department of Molecular/Cellular Neuroscience, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan) ,  Takemoto-Kimura Sayaka (Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency, Saitama, Japan) ,  Abe Manabu (Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, Niigata 951-8585, Japan) ,  Okamura Michiko (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Kondo Yayoi (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Quirin Sean (Department of Bioengineering, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Ramakrishnan Charu (Department of Bioengineering, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Imamura Takeshi (Department of Molecular Medicine for Pathogenesis, Ehime University Graduate School of Medicine, Toon, Ehime 791-0295, Japan) ,  Sakimura Kenji (Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, Niigata 951-8585, Japan) ,  Nemoto Tomomi (Laboratory of Molecular and Cellular Biophysics, Research Institute for Electronic Science, Hokkaido University, Sapporo, Hokkaido 001-0020, Japan) ,  Nemoto Tomomi (Core Research for Evolutional Science and Technology (CREST), Japan Agency for Medical Research and Development, Tokyo, Japan) ,  Kano Masanobu (Department of Neurophysiology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Kano Masanobu (International Research Center for Neurointelligence, The University of Tokyo, Tokyo, Japan) ,  Fujii Hajime (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Deisseroth Karl (Department of Bioengineering, Stanford University School of Medicine, Stanford, CA 94305, USA) ,  Kitamura Kazuo (Department of Neurophysiology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Kitamura Kazuo (Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi 409-3898, Japan) ,  Bito Haruhiko (Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Bito Haruhiko (International Research Center for Neurointelligence, The University of Tokyo, Tokyo, Japan)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 177  Issue： 5  Page： 1346-1360.e24  Publication year： 2019 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： To decipher dynamic brain info...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=19A1311323&from=J-GLOBAL&jstjournalNo=A0707B") }}

Thesaurus term： *image processing ,  action potential ,  parvalbumin ,  Eumetopias jubata ,  dendrite (neuron) ,  neuron ,  synapse ,  Calcium ,  cortex ,  somatostatin ,  axon ,  Mus musculus ,  spike train ,  Interneurons ,  *bioimaging ,  electrophysiology ,  Myomorpha

Author keywords (8)： genetically encoded calcium indicators ,  two-photon Ca²⁺ imaging ,  XCaMP ,  PV recording ,  paired pre- and post-synapse recording ,  non-invasive hippocampal recording ,  ckkap sequence ,  multiplex imaging

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (5)： 脳回 ,  動力学 ,  イメージング ,  多色 ,  エンジニアリング