Art

J-GLOBAL ID：201902252649465846   Reference number：19A0882177

Antitumor Effects and Delivery Profiles of Menahydroquinone-4 Prodrugs with Ionic or Nonionic Promoiety to Hepatocellular Carcinoma Cells

肝細胞癌細胞に対するイオン性または非イオン性促進性を有するメナヒドロキノン-4プロドラッグの抗腫瘍効果および送達プロファイル【JST・京大機械翻訳】

Author (10)： Setoguchi Shuichi (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Watase Daisuke (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Matsunaga Kazuhisa (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Yamakawa Hirofumi (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Goto Shotaro (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Terada Kazuki (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Ohe Kenji (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Enjoji Munechika (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Karube Yoshiharu (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan) ,  Takata Jiro (Faculty of Pharmaceutical Sciences, Fukuoka University, Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan)
Material： Molecules (Web)
Volume： 23  Issue： 7  Page： 1738  Publication year： 2018 
JST Material Number： U7014A  ISSN： 1420-3049  CODEN： MOLEFW  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Hepatocellular carcinoma (HCC)...

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Thesaurus term： effectiveness ,  *prodrug ,  in vitro experiment ,  Safety ,  Vitamin K ,  *antitumor action ,  prevention ,  Proteins ,  cation ,  therapy ,  *hepatoma ,  Chemoprevention
Semi thesaurus term： 予防的化学療法 ,  予後不良 ,  *非イオン性 , 【Automatic Indexing@JST】

Author keywords (5)： prodrug ,  menahydroquinone-4 ,  menaquinone-4 ,  drug delivery system ,  hepatocellular carcinoma

JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Reference (36)：

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Terms in the title (8)： 肝細胞 ,  癌細胞 ,  イオン性 ,  非イオン性 ,  プロドラッグ ,  抗腫瘍効果 ,  送達 ,  プロファイル