Art

J-GLOBAL ID：201902253307051090   Reference number：19A1042177

p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia

p53は高血糖と虚血に関連する内皮機能障害において重要な役割を果たす【JST・京大機械翻訳】

Author (19)： Yokoyama Masataka (Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan) ,  Shimizu Ippei (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Shimizu Ippei (Division of Molecular Aging and Cell Biology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Nagasawa Ayako (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Nagasawa Ayako (Department of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Yoshida Yohko (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Yoshida Yohko (Division of Molecular Aging and Cell Biology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Katsuumi Goro (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Wakasugi Takayuki (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Hayashi Yuka (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Ikegami Ryutaro (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Suda Masayoshi (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Ota Yusuke (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Okada Sho (Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan) ,  Fruttiger Marcus (Institute of Ophthalmology, University College London, London EC1V 9EL, UK) ,  Kobayashi Yoshio (Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan) ,  Tsuchida Masanori (Department of Thoracic and Cardiovascular Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan) ,  Kubota Yoshiaki (Department of Anatomy, Keio University School of Medicine, Tokyo 160-8582, Japan) ,  Minamino Tohru (Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan)
Material： Journal of Molecular and Cellular Cardiology  (J Mol Cell Cardiol)
Volume： 129  Page： 105-117  Publication year： 2019 
JST Material Number： E0538A  ISSN： 0022-2828  CODEN： JMCDAY  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： p53 is a guardian of the genom...

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Thesaurus term： genome ,  Mus musculus ,  Diabetes Mellitus ,  angiogenesis ,  pathological state ,  Up-Regulation ,  effect ,  nitrogen monoxide ,  *ischemia ,  *p53 protein ,  Carcinogenesis ,  human ,  *Endothelium ,  endothelial cell ,  Myomorpha
Semi thesaurus term： 治療標的 , 【Automatic Indexing@JST】

Author keywords (4)： Endothelium ,  Nitric oxide ,  Angiogenesis ,  Vascular disease

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Terms in the title (5)： p53 ,  高血糖 ,  虚血 ,  内皮機能障害 ,  役割