Art

J-GLOBAL ID：201902257274957261   Reference number：19A0393676

Engineering of Corynebacterium glutamicum as a prototrophic pyruvate-producing strain: Characterization of a ramA-deficient mutant and its application for metabolic engineering

原栄養性ピルビン酸産生株としてのCorynebacterium glutamicumの工学:ramA欠損変異株の特性化及び代謝工学への応用

Author (7)： KATAOKA Naoya (Yamaguchi Univ., Yamaguchi, JPN) ,  VANGNAI Alisa S. (Chulalongkorn Univ., Bangkok, THA) ,  PONGTHARANGKUL Thunyarat (Mahidol Univ., Bangkok, THA) ,  YAKUSHI Toshiharu (Yamaguchi Univ., Yamaguchi, JPN) ,  WADA Masaru (Hokkaido Univ., Sapporo, JPN) ,  YOKOTA Atsushi (Hokkaido Univ., Sapporo, JPN) ,  MATSUSHITA Kazunobu (Yamaguchi Univ., Yamaguchi, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 83  Issue： 2  Page： 372-380  Publication year： Feb. 2019 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *metabolite ,  citric acid cycle ,  mutant ,  iron-sulfur protein ,  pyruvate dehydrogenase ,  gene deficiency ,  *Corynebacterium glutamicum ,  *Corynebacterium ,  RamA protein ,  *microorganism ,  aliphatic ketone ,  aliphatic carboxylic acid ,  keto acid ,  hexose ,  aldose ,  dicarboxylic acid ,  aliphatic alcohol ,  secondary alcohol ,  hydroxy acid ,  fatty acid ,  drug
Semi thesaurus term： *Corynebacterium ,  RamA

JST classification (1)： Substance production by microorganisms,cultured tissues/cells in general  (FK03010P)

Substance index (6)： Pyruvic Acid ,  Glucose ,  α-Ketoglutaric acid ,  Lactic acid ,  Acetic acid ,  Succinic Acid

Reference (42)：

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• Stanko RT, Reynolds HR, Hoyson R, et al. Pyruvate supplementation of a low-cholesterol, low-fat diet: effects on plasma lipid concentrations and body composition in hyperlipidemic patients. Am J Clin Nutr. 1994;59:423-427.
• Stanko RT, Robertson RJ, Galbreath RW, et al. Enhanced leg exercise endurance with a high-carbohydrate diet and dihydroxyacetone and pyruvate. J Appl Physiol. (1985). 1990;69: 1651-1656.

Terms in the title (11)： 栄養 ,  ピルビン酸 ,  株 ,  Corynebacterium ,  工学 ,  RamA ,  欠損 ,  変異株 ,  特性化 ,  代謝工学 ,  応用