Art

J-GLOBAL ID：201902258753150867   Reference number：19A1480569

Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment

全身性硬化症における2-カルバ環状ホスファチジン酸(2CCPA)の抗線維症効果:新規治療への寄与【JST・京大機械翻訳】

Author (10)： Higuchi Tomoaki (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Takagi Kae (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Tochimoto Akiko (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Ichimura Yuki (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Norose Takanari (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Katsumata Yasuhiro (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Masuda Ikuko (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Yamanaka Hisashi (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan) ,  Morohoshi Toshiro (SANSHO, Co., Ltd., Tokyo, Japan) ,  Kawaguchi Yasushi (Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan)
Material： Arthritis Research & Therapy (Web)
Volume： 21  Issue： 1  Page： 103  Publication year： 2019 
JST Material Number： U7412A  ISSN： 1478-6362  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Cyclic phosphatidic acid (cPA)...

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Thesaurus term： *fibrous disease ,  human ,  *therapy ,  Extracellular Matrix ,  fibroblast ,  *Cyclic phosphatidic acid ,  antifibrotic effect ,  TGF-beta(1) ,  model mouse ,  Models, Animal ,  skin fibroblast ,  autotaxin ,  amine ,  carboxylic acid ,  nitrogen heterocyclic compound ,  carbamate ,  oligopeptide ,  carboxamide ,  disaccharide ,  pyranoside ,  sulfur heterocyclic compound ,  hydroxy compound ,  carbonic acid derivative ,  peptide antibiotics ,  antineoplastic antibiotics ,  matrix (base) ,  antibacterial drug ,  antimicrobial drug ,  drug ,  adenine nucleotide ,  ribonucleotide ,  cyclic nucleotide
Semi thesaurus term： bleomycin ,  病巣 ,  *全身性強皮症 , 【Automatic Indexing@JST】

Author keywords (5)： Fibrosis ,  Fibroblasts ,  Systemic sclerosis ,  Cyclic phosphatidic acid ,  Treatment

JST classification (3)： Basic medicine on musculoskeletal system  (GG01020B) ,  Immunological reaction in general  (ED03010T) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Substance index (1)： cAMP

Reference (50)：

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Terms in the title (4)： 全身性硬化症 ,  環状ホスファチジン酸 ,  線維症 ,  治療