Art

J-GLOBAL ID：201902260386095084   Reference number：19A0240421

Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche

マイトジェンの競合は開放ニッチにおける精子形成幹細胞ホメオスタシスを調節する【JST・京大機械翻訳】

Author (34)： Kitadate Yu (Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Kitadate Yu (Department of Basic Biology, School of Life Science, Graduate University for Advanced Studies (Sokendai), 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Jorg David J. (The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK) ,  Jorg David J. (Cavendish Laboratory, Department of Physics, University of Cambridge, J.J. Thomson Avenue, Cambridge CB3 0HE, UK) ,  Tokue Moe (Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Tokue Moe (Department of Basic Biology, School of Life Science, Graduate University for Advanced Studies (Sokendai), 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Maruyama Ayumi (Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Ichikawa Rie (Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Tsuchiya Soken (Department of Pharmaceutical Biochemistry, Kumamoto University Graduate School of Pharmaceutical Sciences, Oe-Honmachi, Kumamoto 862-0973, Japan) ,  Tsuchiya Soken (AMED-CREST, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan) ,  Segi-Nishida Eri (Department of Biological Science and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan) ,  Nakagawa Toshinori (Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Nakagawa Toshinori (Department of Basic Biology, School of Life Science, Graduate University for Advanced Studies (Sokendai), 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Uchida Aya (Department of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan) ,  Kimura-Yoshida Chiharu (Department of Molecular Embryology, Research Institute, Osaka Women’s and Children’s Hospital, Osaka Prefectural Hospital Organization 840, Murodo-cho, Izumi, Osaka, 594-1101, Japan) ,  Mizuno Seiya (Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan) ,  Sugiyama Fumihiro (Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan) ,  Azami Takuya (Department of Stem Cells and Human Disease Models, Research Center for Animal Life Science, Shiga University of Medical Science, Seta, Tsukinowa-cho, Otsu, Shiga 520-2192, Japan) ,  Ema Masatsugu (Department of Stem Cells and Human Disease Models, Research Center for Animal Life Science, Shiga University of Medical Science, Seta, Tsukinowa-cho, Otsu, Shiga 520-2192, Japan) ,  Noda Chiyo (Division of Environmental Photobiology, National Institute for Basic Biology, Okazaki 444-8585, Japan) ,  Kobayashi Satoru (Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan) ,  Matsuo Isao (Department of Molecular Embryology, Research Institute, Osaka Women’s and Children’s Hospital, Osaka Prefectural Hospital Organization 840, Murodo-cho, Izumi, Osaka, 594-1101, Japan) ,  Kanai Yoshiakira (Department of Veterinary Anatomy, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan) ,  Nagasawa Takashi (Laboratory of Stem Cell Biology and Developmental Immunology, Graduate School of Frontier Biosciences, Graduate School of Medicine, Immunology Frontier Research Center, World Premier International Research Center (WPI), Osaka University, Osaka 565-0871, Japan) ,  Sugimoto Yukihiko (Department of Pharmaceutical Biochemistry, Kumamoto University Graduate School of Pharmaceutical Sciences, Oe-Honmachi, Kumamoto 862-0973, Japan) ,  Sugimoto Yukihiko (AMED-CREST, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan) ,  Takahashi Satoru (Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan) ,  Takahashi Satoru (Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan) ,  Simons Benjamin D. (The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK) ,  Simons Benjamin D. (Cavendish Laboratory, Department of Physics, University of Cambridge, J.J. Thomson Avenue, Cambridge CB3 0HE, UK) ,  Simons Benjamin D. (Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge CB2 1QR, UK) ,  Yoshida Shosei (Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Yoshida Shosei (Department of Basic Biology, School of Life Science, Graduate University for Advanced Studies (Sokendai), 5-1 Higashiyama, Myodaiji, Okazaki 444-8787, Japan) ,  Yoshida Shosei (AMED-CREST, Japan Agency for Medical Research and Development, Tokyo 100-0004, Japan)
Material： Cell Stem Cell
Volume： 24  Issue： 1  Page： 79-92.e6  Publication year： 2019 
JST Material Number： W3106A  ISSN： 1934-5909  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： In many tissues, homeostasis i...

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Thesaurus term： *stem cell ,  *mitogen ,  robustness ,  forecast ,  *homeostasis ,  modeling ,  *Spermatogenesis ,  Biophysics ,  FGF ,  Anatomy ,  Mus musculus ,  Models, Theoretical ,  *niche ,  *differentiation (biology) ,  *developmental physiology ,  Myomorpha
Semi thesaurus term： 局在化 , 【Automatic Indexing@JST】

Author keywords (7)： stem cells ,  spermatogenesis ,  density homeostasis ,  open niche ,  biophysical modeling ,  mitogen competition ,  fibroblast growth factors

JST classification (3)： Development(=generation)and differentiation  (EJ16020W) ,  Reproductive(=genital)organs  (EJ15020P) ,  Cell physiology in general  (EF02010S)

Terms in the title (7)： マイトジェン ,  競合 ,  ニッチ ,  精子形成 ,  幹細胞 ,  ホメオスタシス ,  調節