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J-GLOBAL ID：201902264115901111   Reference number：19A2825794

Ligand Binding-Induced Structural Changes in the M₂ Muscarinic Acetylcholine Receptor Revealed by Vibrational Spectroscopy

振動分光法により明らかにされたM_2ムスカリン性アセチルコリン受容体におけるリガンド結合誘導構造変化【JST・京大機械翻訳】

Author (10)： Katayama Kota (Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, Japan) ,  Katayama Kota (OptoBioTechnology Research Center, Nagoya Institute of Technology, Japan) ,  Suzuki Kohei (Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, Japan) ,  Suno Ryoji (Department of Medical Chemistry, Kansai Medical University, Japan) ,  Tsujimoto Hirokazu (Department of Cell Biology and Medical Chemistry, Graduate School of Medicine, Kyoto University, Japan) ,  Iwata So (Department of Cell Biology and Medical Chemistry, Graduate School of Medicine, Kyoto University, Japan) ,  Kobayashi Takuya (Department of Medical Chemistry, Kansai Medical University, Japan) ,  Kobayashi Takuya (Japan Agency for Medical Research and Development, Core Research for Evolutional Science and Technology (AMED-CREST), Japan) ,  Kandori Hideki (Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, Japan) ,  Kandori Hideki (OptoBioTechnology Research Center, Nagoya Institute of Technology, Japan)
Material： Journal of Physical Chemistry Letters
Volume： 10  Issue： 22  Page： 7270-7276  Publication year： 2019 
JST Material Number： W3687A  ISSN： 1948-7185  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： M₂ muscarinic acety...

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Thesaurus term： *receptor ,  lipid membrane ,  *vibrational spectroscopy ,  reconstitution ,  spectrum ,  conformational transition ,  *muscarinic receptor ,  infrared spectrophotometry ,  Nervous System ,  lipid ,  molecular mechanism ,  cell response ,  *ligand binding ,  fatty acid
Semi thesaurus term： アゴニスト , 【Automatic Indexing@JST】

JST classification (1)： Solar cell  (NC03084O)

Substance index (1)： Acetylcholine

Terms in the title (5)： 振動分光法 ,  ムスカリン性アセチルコリン受容体 ,  リガンド結合 ,  誘導 ,  構造変化