SUNO RYOJI

スノリョウジ | SUNO RYOJI

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://kmu-medchem.jp/

Research field (4)： Medical biochemistry , Biophysics , Functional biochemistry , Structural biochemistry

Research keywords (7)：シグナル伝達 , X線結晶構造解析 , 膜タンパク質 , GPCR , クライオ電子顕微鏡単粒子解析 , 生化学 , 構造生物学

Research theme for competitive and other funds (20)：

2024 - 2027 睡眠覚醒を制御するオレキシン受容体シグナル伝達機構の全貌解明と選択的薬剤開発
2023 - 2026 慢性掻痒の創薬に向けた中枢痒み受容体GRPR、NMBRの構造基盤の解明
2021 - 2026 Elucidation of the mechanism of rhodopsin functions for optogenetics
2021 - 2024 Multi-scale platform for untangling physiological complexity
2021 - 2024 過渡的タンパク質複合体の高速構造解析プラットフォームの構築

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Papers (31)：

Shun Yokoi, Ryoji Suno, Ayori Mitsutake. Structural and Computational Insights into Dynamics and Intermediate States of Orexin 2 Receptor Signaling. The journal of physical chemistry. B. 2024
Ryoji Suno. Exploring Diverse Signaling Mechanisms of G Protein-Coupled Receptors through Structural Biology. Journal of biochemistry. 2024. 175. 4. 357-365
Kota Katayama, Ryoji Suno. Holistic concepts in GPCR dynamics. Biophysics and Physicobiology. 2024
Kayo Imamura, Ken-Ichi Akagi, Yohei Miyanoiri, Hirokazu Tsujimoto, Takatsugu Hirokawa, Hideo Ashida, Kaori Murakami, Asuka Inoue, Ryoji Suno, Takahisa Ikegami, et al. Interaction modes of human orexin 2 receptor with selective and nonselective antagonists studied by NMR spectroscopy. Structure. 2024. 32. 3. 352-361
Hidetsugu Asada, Dohyun Im, Yunhon Hotta, Satoshi Yasuda, Takeshi Murata, Ryoji Suno, So Iwata. Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor. Structure (London, England : 1993). 2022. 30. 12. 1582-1589

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MISC (58)：

SUNO Chiyo, SUNO Ryoji, NISHIKAWA Ryo, SUZUKI Riko, IWATA Seiya, TAKAI Tomoyo, OGURA Takaya, HIROSE Mika, INOUE Akitoshi, KISE Ryoji, et al. Structural insights into human kappa opioid receptor signaling by biased ligand. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
寿野良二, 森本和志, 豊田洋輔, 野島慎五, 小林(清水)拓也. Structural analysis of prostaglandin receptors to elucidate the signaling mechanism. 日本薬学会年会要旨集(Web). 2023. 143rd
杉浦勇也, 片山耕大, 住井裕司, すずき洸平, 寿野良二, 柴田哲男, 神取秀樹. Infrared spectroscopic study of acetylcholine analogues to elucidate the activation mechanism of acetylcholine receptor M<sub>2</sub>R. 分子科学討論会講演プログラム&要旨(Web). 2023. 17th
寿野良二, 清水(小林)拓也. Structural Biology of Prostaglandin Receptors. 生物物理(Web). 2023. 63. 1
寿野良二, 清水拓也[小林]. プロスタグランジン受容体の構造生物学. 生物物理. 2023. 63. 1. 16-20

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Education (1)：

Professional career (1)：

Work history (8)：

2023/01 - 現在 Kansai Medical University Dept. of Medical Chemistry Associate Professor
2018/10 - 2022/12 Kansai Medical University
2018/02 - 2018/09 Kyoto University
2013/03 - 2018/01 Kyoto University
2010/04 - 2013/02 Kyoto Sangyo University Faculty of Life Sciences

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Committee career (2)：

Awards (3)：

2024/03 - Kansai Medical University Teacher Evaluation Excellence Award
2023/03 - Kansai Medical University Teacher Evaluation Excellence Award
2017/05 - コールド・スプリング・ハーバーアジア fellowship award High-resolution crystal structures of human orexin 2 receptors bound to a selective antagonist EMPA

Association Membership(s) (3)：

日本蛋白質科学会 , 日本分子生物学会 , 日本生物物理学会

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