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J-GLOBAL ID：201902265912715661   Reference number：19A1474871

Magnoliae Cortex extract protects PC12 cells from cytotoxicity induced by hydrogen peroxide or 6-hydroxydopamine through enzyme induction

Magnoliae Cortex抽出物は酵素誘導を通じて過酸化水素または6-ヒドロキシドーパミンにより誘導される細胞毒性からPC12細胞を保護する

Author (6)： Nishiyama Takahito (Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences) ,  Masuda Yasuhiro (Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences) ,  Izawa Tadashi (Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences) ,  Ohnuma Tomokazu (Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences) ,  Ogura Kenichiro (Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences) ,  Hiratsuka Akira (Department of Drug Metabolism and Molecular Toxicology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)
Material： Fundamental Toxicological Sciences (Web)  (Fundam Toxicol Sci (Web))
Volume： 6  Issue： 3  Page： 107-112(J-STAGE)  Publication year： 2019 
JST Material Number： U0596A  ISSN： 2189-115X  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Magnoliaceae ,...
Semi thesaurus term： *cytoprotective effect

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Author keywords (6)： Catalase ,  Hydrogen peroxide ,  6-Hydroxydopamine ,  NAD(P)H:Quinone oxidoreductase 1 ,  Oxidative stress ,  PC12 cells

JST classification (2)： Basic research of other drugs  (GW23010K) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (1)： 6-Hydroxydopamine

Reference (22)：

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Terms in the title (7)： 抽出物 ,  酵素誘導 ,  過酸化水素 ,  6-ヒドロキシドーパミン ,  誘導 ,  細胞毒性 ,  PC12細胞