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J-GLOBAL ID：201902268719418015   Reference number：19A0317268

Subatomic structure of hyper-sweet thaumatin D21N mutant reveals the importance of flexible conformations for enhanced sweetness

Hyper-Sweet Thaumatin D21N変異体のサブ原子構造は甘味増強のための柔軟な立体配座の重要性を明らかにする【JST・京大機械翻訳】

Author (9)： Masuda Tetsuya (Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan) ,  Okubo Kyohei (Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan) ,  Murata Kazuki (Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan) ,  Mikami Bunzo (Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan) ,  Sugahara Michihiro (RIKEN SPring-8 Center, Kouto, Sayo-cho, Sayo-gun, Hyogo, 679-5148, Japan) ,  Suzuki Mamoru (Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan) ,  Temussi Piero Andrea (Department of Basic and Clinical Neurosciences, King’s College London, London, SE59RX, UK) ,  Temussi Piero Andrea (Dipartimento di Chimica, Universita’ di Napoli Federico II, Napoli, I-80126, Italy) ,  Tani Fumito (Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Gokasho, Uji, Kyoto, 611-0011, Japan)
Material： Biochimie
Volume： 157  Page： 57-63  Publication year： 2019 
JST Material Number： B0147A  ISSN： 0300-9084  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： One of the sweetest proteins f...

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Thesaurus term： *steric conformation ,  side chain ,  atomic structure ,  sweetener ,  interaction ,  *sweetness ,  thaumatin ,  hydrogen bond ,  Proteins ,  wild type ,  complementation ,  flexibility ,  electrostatic potential ,  sweet taste receptor
Semi thesaurus term： 原子分解能 , 【Automatic Indexing@JST】

Author keywords (5)： Subatomic resolution structure ,  Sweet-tasting protein ,  Thaumatin ,  Flexible conformation ,  B-factor

JST classification (2)： Molecular structure  (EB03020Y) ,  Other senses  (EJ13040X)

Terms in the title (7)： 変異体 ,  サブ ,  原子構造 ,  甘味 ,  増強 ,  立体配座 ,  重要性