Art

J-GLOBAL ID：201902270048264065   Reference number：19A0666262

トラベクテジンの血管外漏出により皮膚障害を生じた一例

Author (6)： AKEJIMA NAOYA (長崎大 医 整形外科) ,  TOMITA MASATO (長崎大 医 整形外科) ,  MIYATA MICHIAKI (長崎大 医 整形外科) ,  NOMURA KENTARO (長崎大 医 整形外科) ,  UEKI TOMOHIRO (長崎大 医 整形外科) ,  OZAKI MAKOTO (長崎大 医 整形外科)
Material： 整形外科と災害外科  (Journal of West-Japanese Society of Orthopedics & Traumatology)
Volume： 68  Issue： 2  Page： 181-184  Publication year： Mar. 25, 2019 
JST Material Number： Z0437B  ISSN： 0037-1033  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *antitumor drug ,...
Semi thesaurus term： Extravasation

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JST classification (2)： Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Skin diseases  (GF03000Q)

Substance index (1)： Trabectedin

Reference (5)：

• 1) Aoyama, R., et al.: A rare case of severe muscular necrosis due to extravascular leakage of trabectedin-severe tissue damage of trabectedin extravasation. Journal of Cosmetics, Dermatological Sciences and Applications, 8: 6-9, 2018.
• 2) Fidalgo, J.A.P., et al.: Management of chemotherapy extravasation. ESMO-EONS Clinical Practice Guidelines. Ann. Oncol., 23 (Suppl 7): vii167-vii173, 2012.
• 3) Pluschnig, U., et al.: Extravasation emergencies: state-of-the-art management and progress in clinical research. Memo., 9: 226-230, 2016.
• 4) Todd, A., et al.: Recognition of a new chemotherapeutic vesicant: Trabectedin (Ecteinascidin-743) extravasation with skin and soft tissue damage. J. Clin. Oncol., 27(33): 198-200, 2009.
• 5) Verboom, M. C., et al.: Central venous access related adverse events after trabectedin infusions in soft tissue sarcoma patients; experience and management in a nationwide multi-center study. Clin. Sarcoma Res., 7: 2, 2017.

Terms in the title (3)： トラベクテジン ,  血管外漏出 ,  皮膚障害