Art

J-GLOBAL ID：201902270235910912   Reference number：19A1548535

Metformin Promotes the Protection of Mice Infected With Plasmodium yoelii Independently of γδ T Cell Expansion

メトホルミンはγδT細胞増殖と独立してPlasmodium yoelii感染マウスの防御を促進する【JST・京大機械翻訳】

Author (9)： Miyakoda Mana (Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Miyakoda Mana (Research and Education Center for Drug Fostering and Evolution, School of Pharmaceutical Sciences, Nagasaki University, Nagasaki, Japan) ,  Bayarsaikhan Ganchimeg (Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Kimura Daisuke (Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Kimura Daisuke (Department of Health, Sports, and Nutrition, Faculty of Health and Welfare, Kobe Women’s University, Kobe, Japan) ,  Akbari Masoud (Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Udono Heiichiro (Department of Immunology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan) ,  Yui Katsuyuki (Division of Immunology, Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan) ,  Yui Katsuyuki (Graduate School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan)
Material： Frontiers in Immunology (Web)
Volume： 9  Page： 2942  Publication year： 2018 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Adaptive immune responses are ...

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Thesaurus term： *T cell ,  antibody ,  metabolism ,  spleen ,  drug therapy ,  receptor ,  malaria ,  *Plasmodium ,  aliphatic amine
Semi thesaurus term： サイトカイン産生 ,  αβT細胞 ,  適応免疫 ,  *Plasmodium yoelii ,  *γδT細胞 , 【Automatic Indexing@JST】

Author keywords (6)： malaria ,  γδ T cell ,  clonal expansion ,  protection ,  metformin ,  metabolism

JST classification (2)： Immunological reaction in general  (ED03010T) ,  Infectious immunity  (ED03030P)

Substance index (1)： Metformin

Reference (50)：

• World Makaria Report. World Malaria Report 2017.1-196 (2017).
• Crompton PD, Moebius J, Portugal S, Waisberg M, Hart G, Garver LS, et al. Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease. Annu Rev Immunol. (2014) 32:157-87. doi: 10.1146/annurev-immunol-032713-120220
• Struik SS, Riley EM. Does malaria suffer from lack of memory? Immunol Rev. (2004) 201:268-90. doi: 10.1111/j.0105-2896.2004.00181.x
• Ho M, Webster HK, Tongtawe P, Pattanapanyasat K, Weidanz WP. Increased γδ T cells in acute Plasmodium falciparum malaria. Immunol Lett. (1990) 25:139-41. doi: 10.1016/0165-2478(90)90105-Y
• Roussilhon C, Agrapart M, Ballet JJ, Bensussan A. T lymphocytes bearing the γδ T cell receptor in patients with acute Plasmodium falciparum malaria. J Infect Dis. (1990) 162:283-5. doi: 10.1093/infdis/162.1.283-a

Terms in the title (8)： メトホルミン ,  γδT細胞 ,  増殖 ,  Plasmodium ,  感染 ,  マウス ,  防御 ,  促進