Art

J-GLOBAL ID：201902270699480644   Reference number：19A1801127

Plant-based vaccines for Alzheimer’s disease

アルツハイマー病に対する植物に基づくワクチン

Author (2)： ISHIURA Shoichi (Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University) ,  YOSHIDA Taiji (MediHerb Co., Ltd.)
Material： Proceedings of the Japan Academy. Series B. Physical and Biological Sciences  (日本学士院紀要 B)
Volume： 95  Issue： 6  Page： 290-294(J-STAGE)  Publication year： 2019 
JST Material Number： G0485B  ISSN： 0386-2208  CODEN： PJABDW  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Alzheimer Disease ,...
Semi thesaurus term： A .BETA. peptide ,...

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Author keywords (4)： amyloid β protein ,  oral vaccine ,  plant-based vaccine ,  Alzheimer’s disease

JST classification (2)： Nervous system diseases  (GN03000O) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D)

Reference (26)：

• 1) Imtiaz, B., Tolppanen, A.M., Kivipelto, M. and Soininen, H. (2014) Future direction in Alzheimer’s disease from risk factors to prevention. Biochem. Pharmacol. 88, 661-670.
• 2) Selkoe, D.J. and Schenk, D. (2003) Alzheimer’s disease: Molecular understanding predicts amyloid-based therapeutics. Annu. Rev. Pharmacol. Toxicol. 43, 545-584.
• 3) Querfurth, H.W. and LaFerla, F.M. (2014) Alzheimer’s disease. N. Engl. J. Med. 362, 329-344.
• 4) Salloway, S., Sperling, R., Fox, N.C., Blennow, K., Klunk, W., Raskind, M. (2014) Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer’s disease. N. Engl. J. Med. 370, 322-333.
• 5) Doody, R.S., Thomas, R.G., Farlow, M., Iwatsubo, T., Vellas, B., Joffe, S. (2014) Phase 3 trials of solanezmab for mild-to-moderate Alzheimer’s disease. N. Engl. J. Med. 370, 311-321.

Terms in the title (3)： アルツハイマー ,  植物 ,  ワクチン