Art

J-GLOBAL ID：201902272152647069   Reference number：19A0955798

Inhibitory effects of class I antiarrhythmic agents on Na⁺ and Ca²⁺ currents of human iPS cell-derived cardiomyocytes

ヒトiPS細胞由来心筋細胞のNa⁺およびCa²⁺電流に対するクラスI抗不整脈薬の阻害効果

Author (12)： Yonemizu Sayaka (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan) ,  Masuda Keiichiro (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan) ,  Kurata Yasutaka (Department of Physiology II, Kanazawa Medical University, 1-1 Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa 920-0293, Japan) ,  Notsu Tomomi (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan) ,  Higashi Yuhei (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan) ,  Fukumura Kenta (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan) ,  Li Peili (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan) ,  Ninomiya Haruaki (Department of Biological Regulation, Tottori University Faculty of Medicine, Yonago 683-8503, Japan) ,  Miake Junichiro (Department of Pharmacology, Tottori University Faculty of Medicine, Yonago 683-8503, Japan) ,  Tsuneto Motokazu (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan) ,  Shirayoshi Yasuaki (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan) ,  Hisatome Ichiro (Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan)
Material： Regenerative Therapy (Web)
Volume： 10  Page： 104-111  Publication year： 2019 
JST Material Number： U0955A  ISSN： 2352-3204  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *antiarrhythmic drug ,...

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Author keywords (4)： iCell cardiomyocytes ,  class I antiarrhythmic agents ,  Na⁺ channel current ,  L-type Ca²⁺ channel current

JST classification (1)： Basic research of cardioactive drugs  (GW07020N)

Substance index (3)： Mexiletine ,  Pilzicainide ,  Pirmenol

Terms in the title (4)： ヒトiPS細胞 ,  心筋細胞 ,  クラスI抗不整脈薬 ,  阻害効果