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J-GLOBAL ID：201902274717948592   Reference number：19A2914128

A Perspective on the Role of Dynamic Alternative RNA Splicing in the Development, Specification, and Function of Axon Initial Segment

軸索初期セグメントの発生,特定および機能における動的選択的RNAスプライシングの役割に関する展望【JST・京大機械翻訳】

Author (2)： Iijima Takatoshi (Department of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, School of Medicine, Tokai University, Isehara, Japan) ,  Yoshimura Takeshi (Department of Child Development and Molecular Brain Science, United Graduate School of Child Development, Osaka University, Suita, Japan)
Material： Frontiers in Molecular Neuroscience (Web)
Volume： 12  Page： 295  Publication year： 2019 
JST Material Number： U7082A  ISSN： 1662-5099  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Alternative splicing is a powe...

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Thesaurus term： clustering ,  ion channel ,  cell adhesion molecule ,  alternative splicing ,  plasticity ,  neuron ,  homeostasis ,  spectrin ,  adult(development) ,  diversification ,  action potential ,  *axon
Semi thesaurus term： 細胞骨格蛋白質 , 【Automatic Indexing@JST】

Author keywords (8)： alternative splicing ,  axon initial segment ,  Rbfox ,  ankyrin ,  neurofascin ,  spectrin ,  neuronal activity ,  homeostatic plasticity

JST classification (1)： Central nervous system  (EJ12030F)

Reference (51)：

• Allen S. E., Toro C. P., Andrade A., López-Soto E. J., Denome S., Lipscombe D. (2017). Cell-specific RNA binding protein Rbfox2 regulates CaV2.2 mRNA exon composition and CaV2.2 current size. eNeuro 4:ENEURO.0332-16.2017. doi: 10.1523/eneuro.0332-16.2017
• Bender K. J., Trussell L. O. (2012). The physiology of the axon initial segment. Annu. Rev. Neurosci. 35, 249-265. doi: 10.1146/annurev-neuro-062111-150339
• Bennett V., Lorenzo D. N. (2013). Spectrin- and ankyrin-based membrane domains and the evolution of vertebrates. Curr. Top. Membr. 72, 1-37. doi: 10.1016/b978-0-12-417027-8.00001-5
• Berghs S., Aggujaro D., Dirkx R.Jr., Maksimova E., Stabach P., Hermel J. M., et al. (2000). betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system. J. Cell Biol. 151, 985-1002. doi: 10.1083/jcb.151.5.985
• Debanne D., Campanac E., Bialowas A., Carlier E., Alcaraz G. (2011). Axon physiology. Physiol. Rev. 91, 555-602. doi: 10.1152/physrev.00048.2009

Terms in the title (6)： 軸索 ,  初期 ,  セグメント ,  RNAスプライシング ,  役割 ,  展望