Art

J-GLOBAL ID：201902276228059904   Reference number：19A1182504

Ras homolog gene family H (RhoH) deficiency induces psoriasis-like chronic dermatitis by promoting T_H17 cell polarization

Rasホモログ遺伝子ファミリーH(RhoH)欠損はT_H17細胞分極を促進することにより乾癬様慢性皮膚炎を誘発する【JST・京大機械翻訳】

Author (17)： Tamehiro Norimasa (Department of Immunology and Pathology, National Center for Global health and Medicine, Chiba, Japan) ,  Nishida Kyoko (Department of Immunology and Pathology, National Center for Global health and Medicine, Chiba, Japan) ,  Nishida Kyoko (Department of Immunology, Tokyo Medical and Dental University, Tokyo, Japan) ,  Sugita Yu (Department of Immunology and Pathology, National Center for Global health and Medicine, Chiba, Japan) ,  Hayakawa Kunihiro (Department of Immunology and Pathology, National Center for Global health and Medicine, Chiba, Japan) ,  Oda Hiroyo (Department of Immunology and Pathology, National Center for Global health and Medicine, Chiba, Japan) ,  Nitta Takeshi (Department of Immunology and Pathology, National Center for Global health and Medicine, Chiba, Japan) ,  Nakano Miwa (Communal laboratory, National Center for Global health and Medicine, Chiba, Japan) ,  Nishioka Akiko (Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan) ,  Yanobu-Takanashi Reiko (Department of Laboratory Animal Medicine, National Center for Global health and Medicine, Chiba, Japan) ,  Goto Motohito (Department of Laboratory Animal Medicine, National Center for Global health and Medicine, Chiba, Japan) ,  Okamura Tadashi (Department of Laboratory Animal Medicine, National Center for Global health and Medicine, Chiba, Japan) ,  Okamura Tadashi (Department of Infectious Diseases, Research Institute, National Center for Global health and Medicine, Chiba, Japan) ,  Adachi Reiko (Department of Biochemistry, National Institute of Health Sciences, Kawasaki, Japan) ,  Kondo Kazunari (Department of Biochemistry, National Institute of Health Sciences, Kawasaki, Japan) ,  Morita Akimichi (Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan) ,  Suzuki Harumi (Department of Immunology and Pathology, National Center for Global health and Medicine, Chiba, Japan)
Material： Journal of Allergy and Clinical Immunology  (J Allergy Clin Immunol)
Volume： 143  Issue： 5  Page： 1878-1891  Publication year： 2019 
JST Material Number： A0182B  ISSN： 0091-6749  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Ras homolog gene family H (Rho...

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Thesaurus term： differentiation(biology) ,  pathogenesis ,  *psoriasis ,  adaptor protein ,  therapy ,  RT-PCR ,  wild type ,  immunological reaction ,  characterization ,  cellular signal transduction ,  effector ,  T cell ,  mouse(animal) ,  human(primates)
Semi thesaurus term： インターロイキン22 , 【Automatic Indexing@JST】

Author keywords (7)： Psoriasis ,  T cell ,  T_H17 ,  IL-22 binding protein ,  retinoic acid-related orphan receptor γt ,  Nr2f6 ,  T-cell receptor signaling

JST classification (2)： Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Immunological reaction in general  (ED03010T)

Terms in the title (11)： Ras ,  ホモログ ,  遺伝子ファミリー ,  欠損 ,  細胞 ,  分極 ,  促進 ,  乾癬 ,  慢性 ,  皮膚炎 ,  誘発