Art

J-GLOBAL ID：201902276381737954   Reference number：19A0717855

Optimising first- and second-line treatment strategies for untreated major depressive disorder - the SUND study: a pragmatic, multi-centre, assessor-blinded randomised controlled trial

未治療の大うつ病性障害に対する第一および第二線治療戦略の最適化-Sund研究: 実践的,多施設,評価者盲検化無作為化対照試験【JST・京大機械翻訳】

Author (35)： Kato Tadashi (Aratama Kokorono Clinic, Nagoya, Japan) ,  Furukawa Toshi A. (Department of Health Promotion of Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Mantani Akio (Mantani Mental Clinic, Hiroshima, Japan) ,  Kurata Ken'ichi (Kabe Mental Health Clinic, Hiroshima, Japan) ,  Kubouchi Hajime (Kokokara Clinic, Kochi, Japan) ,  Hirota Susumu (Hirota Clinic, Kurume, Japan) ,  Sato Hirotoshi (Harimayabashi Clinic, Kochi, Japan) ,  Sugishita Kazuyuki (Oji Mental Clinic, Tokyo, Japan) ,  Chino Bun (Ginza Taimei Clinic, Tokyo, Japan) ,  Itoh Kahori (Sinsapporo Mental Clinic, Sapporo, Japan) ,  Ikeda Yoshio (Narumi Himawari Clinic, Nagoya, Japan) ,  Shinagawa Yoshihiro (Shiki Clinic, Nagoya, Japan) ,  Kondo Masaki (Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan) ,  Okamoto Yasumasa (Department of Neuropsychiatry, Hiroshima University Graduate School of Biomedical & Health Sciences, Hiroshima, Japan) ,  Fujita Hirokazu (Center to Promote Creativity in Medical Education, Kochi Medical School, Kochi University, Nankoku, Japan) ,  Suga Motomu (Department of Neuropsychiatry, University of Tokyo Hospital, Tokyo, Japan) ,  Yasumoto Shingo (Department of Neuropsychiatry, Kurume University Medical School, Kurume, Japan) ,  Tsujino Naohisa (Department of Psychiatry, Toho University School of Medicine, Tokyo, Japan) ,  Inoue Takeshi (Department of Neuropsychiatry, Tokyo Medical University, Tokyo, Japan) ,  Fujise Noboru (Department of Neuropsychiatry, Kumamoto University Graduate School of Medicine, Kumamoto, Japan) ,  Akechi Tatsuo (Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan) ,  Yamada Mitsuhiko (Department of Neuropsychopharmacology, National Center of Neurology and Psychiatry, Tokyo, Japan) ,  Shimodera Shinji (Center to Promote Creativity in Medical Education, Kochi Medical School, Kochi University, Nankoku, Japan) ,  Watanabe Norio (Department of Health Promotion of Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Inagaki Masatoshi (Department of Neuropsychiatry, Okayama University Hospital, Okayama, Japan) ,  Miki Kazuhira (Miki Mental Clinic, Yokohama, Japan) ,  Ogawa Yusuke (Department of Health Promotion of Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Takeshima Nozomi (Department of Health Promotion of Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Hayasaka Yu (Department of Health Promotion of Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Tajika Aran (Department of Health Promotion of Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Shinohara Kiyomi (Department of Health Promotion of Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Yonemoto Naohiro (Department of Biostatistics, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Tanaka Shiro (Department of Clinical Biostatistics, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan) ,  Zhou Qi (Departments of Clinical Epidemiology and Biostatistics and of Medicine, McMaster University, Hamilton, Canada) ,  Guyatt Gordon H. (Departments of Clinical Epidemiology and Biostatistics and of Medicine, McMaster University, Hamilton, Canada)
Material： BMC Medicine (Web)
Volume： 16  Issue： 1  Page： 103  Publication year： 2018 
JST Material Number： U7435A  ISSN： 1741-7015  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： For patients starting treatmen...

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Thesaurus term： *optimization ,  remission ,  confidence interval ,  *depression(disease) ,  side effect ,  antidepressive drug ,  *depression(symptom) ,  base line ,  *randomized controlled trial ,  titration ,  *therapy ,  nitrogen heterocyclic compound ,  polynuclear aromatic compound ,  alpha adrenergic agonist ,  alicyclic compound ,  aromatic chlorine compound ,  secondary amine
Semi thesaurus term： 共変量 ,  スコア , 【Automatic Indexing@JST】

Author keywords (4)： Major depressive disorder ,  Antidepressive agents: first-line treatment ,  Second-line treatment ,  Randomised controlled trial

JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Molecular genetics in general  (EC02010J)

Substance index (2)： Mirtazapine ,  Sertraline

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• Depression: the treatment and management of depression in adults (partial update of NICE clinical guideline 23); 2009; CR4; citation_publisher=National Institute for Clinical Excellence
• Lancet; Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis; A Cipriani, TA Furukawa, G Salanti, JR Geddes, JP Higgins, R Churchill, N Watanabe, A Nakagawa, IM Omori, H McGuire; 373; 2009; 746-758; 10.1016/S0140-6736(09)60046-5; citation_id=CR5

Terms in the title (9)： 治療 ,  大うつ病性障害 ,  治療戦略 ,  最適化 ,  研究 ,  施設 ,  評価 ,  盲 ,  無作為化対照試験